r ' Alcohol and the Human Brain. WHAT JOSEPH COOK BAYS ABOUT IT. Cassio's language iu Othello is to-day adopted by cool physiological science: "O God, that men should put an enemy in their mouths to steal away their brains!" Central in all discussion of the influence of intoxicating drink upon the human brain is the fact that albuminous sub stances are hardened by alcohol. I take the white of an egg, and as you sec turn it out in a fluid condition into a goblet. The liquid is a viscous, glue-like sub stance, largely composed of albumen. It is made up of pretty near the same chem ical ingredients that constitute a large part of the brain and nervous system, and of many other tissues of the bo-.ly.— Forty per cent, of the matter in the cor puscles iu the blood is albumen. lam about to drench this white of an egg with alcohol. I have never performed this ex periment before ami it' may not succeed, but so certain am I that it will that 1 pro pose never to put the bottle to my lips aud introduce into my system a liend to steal away my brains. If you will fasten your attention 011 the single fact that alcohol hardens Ibis albu minous aubstar.ee with which I place it iu comact, you will have in this single stratcgetie circumstance an explanation of most of the ravages upon the blood and nerves and brain. I beg you to no tice that the white of an egg iu the goblet docs not become hardened by exposure to the air. I have allowed 11 to lie ex posed for a time, in order that you may see there is no ledgerdemain in the ex periment. I now pour alcohol upon this albuminous fluid, and il the result here is what it has been in other cases, I shall very soon be able to show you a pretty good example of w hat coagulated albu men is iu the nervus system aud blood corpuscles. You will lind this white of an egg gradually so hardened that you can take it out without a fork. I notice al ready that a mysterious change in it has begun. A strange thickening shoots through the fluid miss. This is your moderate drunkard that I am stirring up now [Laughter.] There is 3 our tippler, a piece of him [holding up a portion of the coagulated mass upon the glass pestle.] The coagulation of the substance of the brain goes on. lam stirring up a hard drinker now. The infinitely subtile laws ofchemisiry take their course. Here is a man, [holding up a large part of the co agulated mass] whose brains are so leath ery that he is a beast and kicks his wife to death. lam stirring up i i this goblet now the brain of a hardened sot. On this prongless rod, I hold up a large part of the white of an egg which you saw poured into the glass as a fluid. Here is a man, [holding up a larger mass] who has he numbed his conscience and his tcison both, and has begun to he dangerous to society from a disease I br: in. Wherever alcohol touches this albuminous sub stance, it hardens it, and it docs so by ab sorbing and fixing the water it contains. I dip out of the goblet, now your man who has delirium tremens. Ilere is what was ouce a fluid, rolli g easily to right and left, and now you have the leathery brain aud the hard heart. "Make the btd easy, Mr. 15.," said old Uncle Abe to the undertaker, who was preparing the collln lor his aged wife. "Make the bed easy, for her old bones are tender and soft, and a hard bed will hurt them." He forgot for a moment that old, gray-haired man. that she was dead—that the old bones had done aching forever. Sixty-four years had she walked by his side a true and loving wife. Sixty-four years! Just think of it, in this age of di vource. Sixty-four years had they dwelt under the same sorrows of life; together mourned over the coflin of their first-born together rejoiced in tiie prosperity of ther sons and daughters, and now she has left him alone. No wonder he forgot. Her loving hauds had so long cared for him, 1 for he had been the feebler of the two. "Until death do us part," said the mar riage service that had united them so many years ago. Death had parted them, but the love still survived. Tenderly had he cared for her all these years, and now tenderly did he watch the making of the last bed of this still loved wile. He had bravely breasted the storm of life with her by his side, but now that she was gone he could not live, and in a few days they laid him by her side. jn KMOVAL. CI/AS. M. IIALL I lias removed his Law and Insurance Otlice to 2d floor, over oflice of ELSBREE AND SON, North side of Public Square, To wand a, 011 same floor with I. M'PHKTISON, Esq., and PATHICK & FOYLK. pOH IJYSUR.I.VC Against TMi-e ! in old, reliable, firmly established and honorube criripani"s, viith MILLIONS OK CAPITAL 1 call .ipon f. ,11. Il.ti.lf>, Attorney-nt-Law, To wanda, Pcnu'a. jam 18. JPRET SAWING. All kinds of Fancy Woods for use of Amateurs kept for sale by the undersign ed. WHITE HOLLY, ROSEWOOD, BIRDS-EYE MAPLE, WALNUT, HUNGARIAN ASH, EBONY, &C., &C., Continually on hand. Also all varieties ol HINGES, SCKKWB, I*lXB, SAWS, ETC. Send for price list, A. BEVERLY SMITH, Reporter Building. Y ICR'S ILLUSTRATED FLORAL GUIDE, a beautiful work of 100 pa pages, One Colored Flower Plate, and 500 Illustrations, with Descriptions of the Best Flowers and Vegetables, with prices of seeds, and how to grow them. All for a FIVE CENT STAMP. In English or German. Viek's Seeds are the best in the world. FIVE CKNIH will buy the FLOUAL GUU>E, telling how to get them. The Flower and Vegetable Garden, 17.5 pages, Six Colored Plates, and many hun dred Engravings. For 50 cents in paper covers; §I.OO in elegant cloth. Iu Ger man or English. Vick's Illustrated Monthly Magazine— -32 Pages u Colored Plate in every num ber and many fine Engravings. Price §1.25 a year; Five Copies for §5.00 Specimen Numbers sent for 10 cents; 5 trial copies for 2.5 cents. Address. JAMES VICK, Rochester, N. Y. p.*/f .11 FOR S.I I.E. A farm of 150 acres uear Wyalusinr ) Pa., Oont'Ur.d of improved land* 125 acres ; good barn, fine orchard, well watered, with four nil leu of Le nigh ViUlay railroad, ia uner cent of cultivation. Will be mild at reasonable price, or AM' CIIA NGEI) FOR TO WJf PR 0 PER TV. Inquire of CIIAS. M HALL, At ney-at-Law Towandu, Pa. Jan. 18. YYVTLY REVIEW! Only Twenty-Five CeaU sx Month. TRY IT? Vertical Peed. As usual, the Vertical Feed Sewing Machine took First Pre i % I mium, at the late county Fair. 1831. TIIE CULTIVATOR 1330. ANI) Countr.v Gentleman. The Best of the AGRICULTURAL WE EK LI Rvs. It In UNSURPASSED, If not UNRQUALED, for he Amount and Variety of tin; PRACTICAL INFORMA TION it contain*, and for the Ability and Extent of its CORUKHPONDENCK— in the Three Chief Direction* of Farm Crops and Processes, Horticulture au-.l Fruit-Frowing, Live Stock and Dairying— while it also includes all minor dcpatmcnts of rural interest, stich us the Poultry Yard, Entomology, Bee-Keeping, Ui ecu house and drapery. Veterinary Replies, Farm Questions nnd Anstvi rs, Fireside Reading, Domestic Economy, and a summary of the News of the Week. It* MARKET REPORTS are unusually complete, and more information can be gathered from it* column* than from any other source with regard to the Prospects of the Crops, as throwing light upon one of the most important of all questions— When to Buy and When to Bell. It il liberally illustrated, and constitutes to a greater degree than any of its contemporaries A LIVE AGRICULTURAL NEWS I' \I'KK Ol iie-er-failing interest both to Producers and Con sumers of every class. The COUNTRY GENTLEMAN is published Weekly on the following terms, when paid strictly In ad vance: One Copy, one year, $2.50; Four Copies, $lO, nnd an additional copy for the year free to the sender of the L'lul •• Ten Copies, S2O, and an additional coj>y for th year free to the sender oj the Cltth. For the year 1883, these prices include a copy 01 the ANNUAL REUISTEROF RURAL AFFAIRS, to each übseriber—a book of 141 pages and about 120 ne graving*—a gift by the Publishers. Alt NEW Subscriber 9 fur 1880, fatying in ad vance now, will receive the paper WEEKLY", from receipt of remittance to January let, 1830, with out charge.] HSrdpechnen copies of the paper free. Adddress, LUTHER TUCKER & ts<)N, Publisher*, Albany, N. Y. P"A>R. THE PRESIDENTIAL YEAR. 44 THE LEADING AMERICAN NEWS TAPE 11" THE NEW YORK TRIBUNE FOR 1880. During tlw coming Presidential year The Tribune will be a more effective agency than ever for telling Die new* best worth knowing, and for enforcing sound politics. From the day the war closed it has been most anxious for an end of sectional strife. But it saw two years ago, and was the first persist ently to Proclaim the new danger to the country from the revived alliance of the Solid South and Tammany llall. Against that danger it sought to rally the old party of Freedom and the Union Ii by demauding the abandonment of personal dislikes, and set the example. It called for an end to attacks upon each other Instead of the eneuiy; and for the heartiest agreement upon wliatevre fit candidates the nuyority should put up against the common foe. Since then the tide of disaster has been turned back; every doubtful state has been won, and the omens for National victory were never more cheering. TIIK TRIBUNE'S POSITION. Of The Tribune's share in all this, those speak most enthusiastically who have seen most of the struggle. It will faithfully portray the varnlng phases of the campaign now beginning. It will earnestly strive that the party of Freedom, Union and Public Faith may select the man surest to win, and surest to make a good President. Put in this crisis it can conceive of no nomination this party could make that would not be preferable to the best that could possibly be supported by the Solid South j and Tammany Ilall. The Tribune is now spending much labo and money than ever before to hold the distinction it has enjoyed of the largest circulation among the bent people. It secured, and means to retain it by be coming the medium of the best thought and the voice of the best conscience of the time, by keeping abreast of the highest progress, favoring the freees discussions, hearing all sides, appealing always to the best intelligence and the purest morality, and re. fusing to carter to the tastes of the vile or the preju . dices of the ignorant. ' SPECIAL FEATURES. The distinctive features of The Tribune are known to everybody. It gives all the news. It lias the best correspondents, and retains them from year to year, It is the only paper that maintains u special telegraphic wire of its own between its otlico and Washington. Its scientific, literary, artist!a and re ligious intelligence is the fullest. Its book reviews are the best. Its commercial and financial ne** T s is the most exact Its type is the largest; and us ar langement the most systematic. THE SEMI-WEEKLY TRIBUN is by far the most successful Semi-Weekly In-the country, having fonr times the circulation of any other in New York. It is especially adapted to the large class of intelligent, professional or business readers too far from New York to depend on our papers for the daily news, who nevertheless want the editorials, correspondence, book reviews, scien tific matter, lectures, literary miscellaney, etc,, fur which The Tribune is famous. Like The Weekly > it cont.i'ns sixteen pages, and is in convenient form or binding, THE WEEKLY TRIBUNE , remains the great favorite of our substantial country population, and has the largest circulation of any Weekly issued from the olliee of a Daily paper ia New \ork, or, so far as we know, in the United States, li revises and condenses all the news of the week into more readable shape. Its agricultural de partment is more carefully conducted than ever, and it has always been considered the best. Its market reports are the otlicial standard for the Dairymen's • Association, ami have long been recognized author ity on cattle, grain and general country produce, i'here are special departments for the young and for 1 household interests; the new handiwork department i already extremely popular, gives unusually accurate and comprehensive instructions in knitting, crochet ng, and kindrid subjects; while poetry, fiction and he humors of the day arc all abundantly supplied. I he verdict of the tens of thousand old readers who have returned to it during the past year is that tli y find it better than ever. Increasing patronage a' d lacilitias enable us to reduce the rates to the low point we have ewr touched, and to ofier the must amazing premiums yet given, as follows: TERMS OF THE TRIBUNE, Pontage free in the United States. DAILY TRIBUNK $lO 00 TUB SEMI-WEEKLY TRIBUNE. Single copy, one year $3 Five copies, one year *2 50 each Ten copies, one year 2 00 each THE WEEKIY TRIBUNE. • Single copy, one year $2 00 Five espies, one year 1 50 each Ten copies, one year 1 00 ouch And number of copies ol either edition above ten at the same rate. Additions to clubs may be made at any time at elub rates. Remit by Draft on New York, I'ost Oitiee Order, or in Registered letter. AN AMAZING I'REMHJM. To any one subscribing for The Weekly Tribun* for five years, remitting us the price, $lO, and $ more, we will send Chamber's Encyclopedia, tar abridged, in fourteen volumes, witli all the revisions of tiie Edinburgh edition of 187J, and with six ad ditional volumes, covering American topics not fully treated in the original work;—tlic whole embracing oy actual printer's m •sureinent, tuelve per vent more matter than Apple ton's Cyclopedia, which sells for $80! To the 15,000 readers who procured from us tlie Webster Unabridged premium we need only say that while this otter is even more liberal, we shall carry it out in a manner equally satisfactory, i'he following are the terms in detail : For sl2, Chamber's Encyclopaedia, A Library of Universal Knowledge, 14 vols., wi.li < dltlons on American subjects, b separate vols,, 20 vols, in ali, substantially bouud in cloth, and l'he Weekly Tri bune 5 years, to one s 1 ,'scriber. For $lB, Chamber's Encyclopaedia, 20 vols., above, and The Scini-Weekly Tribune & years. For $lB, Chamber's Encyclopaedia, 20 vols., an above, and ten copies of The Weekly Tribune one year. For $27, Chamber's Encyclopaedia, 20 vols, above, and twenty copies of The Weekly Tribune one year. For S2O, Chamber's Encyclopaedia, 20 vols., an above, and the Daily Tribune two yuars. The books will in all cases be sent at the subscri ber's expense, but with no charge Ur packing. We shall begin sending them in the ord l in which sub scriptions have been received on the 1 t of January, when ccriai.ily five, and perhaps six, volumes will be ready, and shall send, thenceforth, by exprcssor mail, as subscribers may direct. The publication will continue at the rate of two volumes per mouth, concluding in September next, A MAGNIFICENT GIFT! Worcester's Great Unabridged Dictionary Fr^e! The New \ ork Trlbuno will send at subscriber's expense fur freight, or deliver in New York City KitEE, Worcester's Great Unabridged Quarto Illus trated Dictionary, edition of 187s, the very latest and very best edition ot tiie great work, to any oue re rnlttlng $lO for a single five years' subscription In advance . r five on J year subscriptions to The Weekly, or sls tor a single*five years' subscription in advance or five onu year subscriptions to The Semi Weekly, or, one year's subscription to The Dally, or, S3O for a single throe year's subscription in advance to The Daily Tribune, For one dollar extra the D'.ctloaa y an be sen* by mail to any part of the Uuited States, while lu short distances the expense is much cheaper. Address THK TRIBUNE, New York
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