A46-Lancaster Farming, Saturday Poultry Basic Research Dr. Sally E. Johnson, Assistant Professor, Developmental Biology Penn State Most of us associate chicken with a source of food. But, in re ality, the chicken serves many purposes, including that of experi mental model. Historically, avian embryos represent the classical develop mental biology model system. Avian embryos develop in a rapid fashion reminiscent of most verte brate animals including humans. And, due to their unique packag ing system, chick embryos can be easily monitored and observed throughout the course of gesta tion. In the mid 19505, two leading scientists documented the mor phological changes that occur dur ing the course of avian develop ment To this day, the develop SHADE TREES for Farm & Industry Red Oak, Pin Oak, Sugar Maple, Ash, Native Red Maple, Locust & More. 2" to 4" Caliper - 13' to 16' Some “Park Grade” Trees Many Pre-Dug for Summer Planting. 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Hamburger and Hamilton serves as a universal handbook for com parative staging of avian embryos. They were one of the first groups to note that the chick heart per forms rhythmic contractions with in the first three days of incuba tion, eye coloration occurs after five-day, and rudimentary feathers are present after nine days. Through their recorded observa tions of avian development, our understanding of the processes of fetal development in humans has been greatly enhanced. In vertebrates, regions of cells respond to their surrounding envi ronment in an instructive fashion, thus becoming committed to a specific cell fate. With regard to cardiogenesis (heart formation), the inductive signal to become a cardiocyte (heart cell) is received within the first 18 hours. After ex- *80 ..*140 each Evergreen Trees Also Available 95 Leisey Road Denver, Lancaster County, Pa 17517 717-336-5515 pansion of the cardioblast popula tion, the cells cease replication and begin to synthesize the pro teins necessary for contraction. The cells align to form a tube structure that ultimately loops and fuses to form the four-chambered heart One of the ongoing projects in our lab is to discern the mechanis tic basis for early heart formation, spedifically, what tells a cell to be come a cardiocyte. Through ex plant experiemnts and tissue graft ing, several small proteins have been identified as candidate-in ducing agents. By characterizing the factors that elicit a response in normally non-cardiogenic cells, we can de termine the functional role of cer tain growth factors and determine the means by which they promote heart formation. One of the recently discovered factors that promotes cardiogene sis is a protein called bone mor phogenic protein (BMP2). BMP2 is one of several growth factors which also is intricately involved in regulating formation of the skeleton. Interestingly, ectopic delivery of BMP2 to cells normally not fated to become cardiocytes in duces expression of genes charac teristic of cardiocytes. This would suggest that one means of promot ing heart formation is through lo calized production of BMP2. The ability of BMP2 to act on two dis F. 0.8. Denver PA Quantity Discounts jM PUBLIC AUCTION jM . *Tj ? m At Paradise Sales Barn, Paradise, Pa. pb Directions: Approximately 8 miles East of Lancaster, PA on Route 30 turn on Meadow Lane to sale on right! _ . _ 9:00 A.M. ntH (Hn 9:00 A.M. Forklifts Iffi ■ <Ult-Wood & Metal Working Equip JP THURS., AUGUST 27, 1998 9:00 A.M. Approx. 21 Forklifts 20,000 lb Hyster Model H2OO ES 2 stage mast, side shift, dual pneumatic tires, Perkins diesel powered, air brakes, cab, 10,0001 b Clark Model Triple Mast Side Shift. 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Hayes Jr. on Thursday visited the Farmer’s Pride plant here to announce the shipment to Japan of more than 100,000 pounds of Bell & Evans chicken - an agreement reached as a result of Gov. Tom Ridge’s trade mission to Asia last year. “Gov. Ridge's trade mission opened the door of Pennsylvania agricultural products to move into Japan,” Hayes said. “The relationships we established during the mission have been invaluable in helping companies such as Bell & Evans to expand their marketing opportunities. “Demand for poultry in Japan is high, and Japanese con sumers value high-quality, all natural meats. Pennsylvania food products are well-known in Japan, and we believe there can be significant trade expansion there.” tinctly different systems further demonstrates the complexity of embryonic development In summary, the avian embryo provides us with a remarkable tool which can provide insight into many developmental questions. By taking advantage of the avian model, key issues regarding hu man disease can be addressed. Wood & Metal Working Equip. Hayes and Scott Sechler, president of Bell & Evans, signed a product certificate veri fying that the poultry is “Pennsylvania raised and processed.” Each shipment will carry a certificate. Bell & Evans chickens are totally grain fed in environmentally controlled houses. Processed by Farmer’s Pride, the Bell & Evans chicken is being shipped from Fredericksburg to Nissho lawi Corp. in Tokyo for distribution to upscale food markets and restaurants throughout Japan. Sechler said the poultry will be freezer-packed and trucked to Seattle, then transported by ship to Japan. Sechler followed up on con tacts made by Hayes in Japan, and several Japanese food industry representatives have visited the Fredericksburg plant and placed orders. Established in 1939, Farmer’s Pride has nearly 600 employees and processes 130,000 chickens daily, market ing in 22 states throughout the Eastern United States. LANCASTER EQUIPMENT ELAM S. STOLTZFUS Terms bv
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