fi Lancaster Farming, Saturday, August 2. 19(H)
Breakthrough in Marek's Disease Studies
Reported By Merck Sharp & Dohme Researchers
Itesc.nch .it the Meick Sharp
A. Dohnu* Research L'aboi atones
is utilizing two important bieak
thloughs in the study of Maiek’s
disease This disease costs Unit
ed States poultiy pioduceis an
estimated 200 million dollars a
year. These cutical bieak-
Ihioughs arc the ability to grow
the herpesvirus associated with
Maiek’s disease in tissue culture
cells, and the development of
simple serologic tests Because
of these advances, scientists now
have the tools necessary foi lap
id advancement in the contiol of
the disease, tepoiled Di Theo
doie A Maag, supeivisor of ic
seaich in avian leukosis at Mei
cl.
Dr Maag has wntlen about
Maiek’s disease in the cunent
issue of The Merck Agncultuial
Memo, published as a seivice to
animal agucultuie bv Feed Pio
ducts, Meick Chemical Division
Marek’s disease is essentially a
ccnglomeiation of tumoious like
disoideis of joung buds Skin,
neives. livei spleen, kidney,
heait and muscle aie involved
Although tumois and associated
conditions aie comparatively
new pioblems to the broiler in
dustiy, they aie now the major
disease of broilei, as well as le
placement bads, bieedei or lay
ei opeiations
Marek leseaich at Merck be
gan several yeais ago when in
vestigatois worked with a bi oil
er from Delmaiva They isolat
ed a strain, now known as MSD
1, which showed only neural and
skin lesions
Investigatois hoping to isolate
the disease-causing agents be
lieve that a heipesvuus is closely
associated with Maiek’s disease
A lew reseai chei*s‘, including Dr
Maag, believe that at least one
other virus is involved
Accoiding to Dr Maag’s article
in the Agricultural Memo, Mai
ek’s disease may be at least two
disease syndiomes One is mfiam
matoiy, seen as uncomplicated
netve and skin lesions The sec
ond is lymphoprolifeiative, and
is lecognized by neoplastic-like
lesions of the kidney, livei,
sp'een, gonads, muscle and
heait Susceptibility appeals to
be diffeient for each bleed, and
the method of infection may also
differ
Bad-to-bud tiansmission is
P'obably limited to close con
tacts and lesults mainly fiom m
Hunter Safety
Requirement
The Pennsylvania Game Com
mission this week again lemmd
ec youths of the hunter safety
tiaimng lequnemenl foi pinch
asing a hunting license
Aitei September 1 1969 no
limiting license shall be issued tc
anv pei son undei the age of
si'ieen vear= unless he p e=enl' 3
evidence that he has held o
.untmg hcen-e i==ued b' the 1
i
common..edGh o f Pennsylvania
O) anothei state map or yea’
oi a ceitifiCdte sho.vmc ih<.‘ ‘he.
, ; outh hdS satisfactory comnlet
a hunter safety comm surh a.
<dmimsteied by the Pennsylvan
a Game Commission
Thousands of youths have al
3 <-adv taken advantage of eaihei
oppoilunities to complete the
huntei safety requnement Ad
mlional youngsteis will have tak
eji the couise befoie the sum
mei ends, so that they will be
jble to qualify foi the 1969-70
minting license which will be
(tiective Septembei 1
tnvone having questions con
<ll ning the pi ov isions of the new
«» -hould consult vnth a local
factions through the lespiratoiy docs not influence M.nck’s di
(i act. On the othei hand, egg- scasc.
liansmission is piobable but not
confirmed.
One thing isccitam, the disea- ionics aie possible and wanant
se is costly. In addition to econ- some hope, says Dr Maag
omic losses clearly attributable The immunological appioach,
to Marek’s disease, the poultiy appeals to offer the gieatest
producer may suffer secondary possibility of success m the neai
losses. For example, Maiek’s futuie The genetic approach will
disease impairs the birds’ probably have limited success,
mechanism for resistance to but should be tried At present,
other disease. Therefore, buds it is the only method that has
haiboring Marek’s disease aie pioved fruitful The thud ap
more susceptible to othei mfec- pioach is that of piophylaxis 01
tions agents, coccidiosis being therapy with dings So far all
foremost This could explain why attempts to attack virus diseases
coccidiosis is often associated and cancer with dings have been
with Maiek’s disease But which extiemely disappointing How
comes first 9 Dr Maag believes evei. as scientific knowledge in
itial Maiek’s disease induces the oeases, joint effoits of chemists
occunence of clinical coccidiosis and biologists may one day be
and not vice veisa Coccidiosis icwaided
|Red Rose
■ DAIRY FEEDS
On pasture ... and in the barn ...
your cows NEED MINERALS!
THESE DEALERS CAN SERVE YOU WITH YOUR NEEDS j
Walter Binkley & Son
Brown & Rea, Inc.
Elverson Supply Co.
Elverson
Henry E. Garber
R. D. 1, Elizabethtown, Pa.
L. T. Ge»b Estate
Manheim
I. B. Graybilf & Son
Refton Strasburg
Review m 2 fuluie methods to
contiol Mmck's disease, three
#
Red Rose Free-Choice Mineral is recommended where there is
heavy use of corn silage* Red Rose Super Miheral is designed for
dairy herds where legume roughage is fed. Be sure include
Red Rose Minerals in your feeding program.
Lititz
Atglen
Pin due aaionom.M Staiilm \
p.,.i liei says that Com Hell faim
eis can apply potassium and
phosphoius at times other than
plant mu and still depend on high
yield*
In the \ugust September
(1969) issue of Crops and Soils
Magazine. Baiber tepoits on a
sixteen-year experiment at the
Pm due Agronomy Faim, where
both broadcast and row applica
tions of phosphoius and potas
sium were studied
In both the i ow and broadcast
applications of phosphoius. corn
yields the fourth year after ap
hcation vveie almost as high as
yields the yeai the fertilizer was
applied Thus potassium could
be applied on the test soil at any
convenient time and still be used
eFectnely
Bioadcast applications of phos
phoius vveie moie effective in
pioducing high corn yields than
weie row applications alone.
Phosphoius applied b\ the low
FEED YOUR COWS
the best your know how!
Red Rose Dairy Feeds . . . and Red Rose Supplements . . ,
are the feeds you need! They provide all the nutrients cows
need for maintenance and put more milk in the pail.
Take Red Rose 14 Test-Cow Feed, for example. This
course-textured all purpose feed can be fed to your milk
ing cows, dry cows, calves and bulls. You can feed it all
seasons but it's especially helpful to keep appetites from
lagging during warm weather. . |
Other Red Rose Dairy Feeds are available in many protein’
levels. Select the one that suits your particular need and
feed with a satisfaction you have never known before! J
E. Musser Heisey & Son
R. D.-#2, Mt. Joy, Pa.
Heistand Bros.
Elizabethtown
Red Rose Form
Service, Inc.
N. Church St., Quarryvilie
David 6. Hurst
BowmansviHe
Martin's Feed Mill; Inc. *
R. D. 3, Ephrata, Pa.
Mountville Feed Service
Mountville
Purdue Agronomist'
Reports Experiment
m
itici fw-ctl corn yields ton bushel?
.11*. .u io Wheie phosphorus was
hio.idun and plow<sQvjjndetv
yields wcie as much as iftte’bush
els hmher than the best yield?
bom iow application of eqmva
lent amounts.
Bioadcast applications woikod
well with potassium, also, but
the Pm due researchers found
potassium less flexible than phos
phorus There was greater fixa
tion by the soil and greater re
moval by the crop A single po
tassium application was found
to be relatively effective for two
years. This means that there iy
still flexibility in the time of ap
plication. even though the resi
dual effects of potassium are
not as great as those for phos
phorus
Many farmers are already us
mg this system of fertilization
with excellent results, and
though it may not work foi all
soils. Barber believes it applies
to a large poition of the Corn
Belt. \t the lates of fertilizer
used today, he says, phosphoius
and potassium can be appl.ed
mainly as bioadcast applications.
Musser Forms, fnc.
Columbia
Musser's Mil!
The Buck
Chas. E. Saucier & Sons
Terre Hill
Ammon E. Shelly
Lititz
E, P. Sports, Inc.
Honey Brook
H, M. Stauffer & Sons, ,
Inc.
Witmer