fi Lancaster Farming, Saturday, August 2. 19(H) Breakthrough in Marek's Disease Studies Reported By Merck Sharp & Dohme Researchers Itesc.nch .it the Meick Sharp A. Dohnu* Research L'aboi atones is utilizing two important bieak thloughs in the study of Maiek’s disease This disease costs Unit ed States poultiy pioduceis an estimated 200 million dollars a year. These cutical bieak- Ihioughs arc the ability to grow the herpesvirus associated with Maiek’s disease in tissue culture cells, and the development of simple serologic tests Because of these advances, scientists now have the tools necessary foi lap id advancement in the contiol of the disease, tepoiled Di Theo doie A Maag, supeivisor of ic seaich in avian leukosis at Mei cl. Dr Maag has wntlen about Maiek’s disease in the cunent issue of The Merck Agncultuial Memo, published as a seivice to animal agucultuie bv Feed Pio ducts, Meick Chemical Division Marek’s disease is essentially a ccnglomeiation of tumoious like disoideis of joung buds Skin, neives. livei spleen, kidney, heait and muscle aie involved Although tumois and associated conditions aie comparatively new pioblems to the broiler in dustiy, they aie now the major disease of broilei, as well as le placement bads, bieedei or lay ei opeiations Marek leseaich at Merck be gan several yeais ago when in vestigatois worked with a bi oil er from Delmaiva They isolat ed a strain, now known as MSD 1, which showed only neural and skin lesions Investigatois hoping to isolate the disease-causing agents be lieve that a heipesvuus is closely associated with Maiek’s disease A lew reseai chei*s‘, including Dr Maag, believe that at least one other virus is involved Accoiding to Dr Maag’s article in the Agricultural Memo, Mai ek’s disease may be at least two disease syndiomes One is mfiam matoiy, seen as uncomplicated netve and skin lesions The sec ond is lymphoprolifeiative, and is lecognized by neoplastic-like lesions of the kidney, livei, sp'een, gonads, muscle and heait Susceptibility appeals to be diffeient for each bleed, and the method of infection may also differ Bad-to-bud tiansmission is P'obably limited to close con tacts and lesults mainly fiom m Hunter Safety Requirement The Pennsylvania Game Com mission this week again lemmd ec youths of the hunter safety tiaimng lequnemenl foi pinch asing a hunting license Aitei September 1 1969 no limiting license shall be issued tc anv pei son undei the age of si'ieen vear= unless he p e=enl' 3 evidence that he has held o .untmg hcen-e i==ued b' the 1 i common..edGh o f Pennsylvania O) anothei state map or yea’ oi a ceitifiCdte sho.vmc ih<.‘ ‘he. , ; outh hdS satisfactory comnlet a hunter safety comm surh a. <dmimsteied by the Pennsylvan a Game Commission Thousands of youths have al 3 <-adv taken advantage of eaihei oppoilunities to complete the huntei safety requnement Ad mlional youngsteis will have tak eji the couise befoie the sum mei ends, so that they will be jble to qualify foi the 1969-70 minting license which will be (tiective Septembei 1 tnvone having questions con <ll ning the pi ov isions of the new «» -hould consult vnth a local factions through the lespiratoiy docs not influence M.nck’s di (i act. On the othei hand, egg- scasc. liansmission is piobable but not confirmed. One thing isccitam, the disea- ionics aie possible and wanant se is costly. In addition to econ- some hope, says Dr Maag omic losses clearly attributable The immunological appioach, to Marek’s disease, the poultiy appeals to offer the gieatest producer may suffer secondary possibility of success m the neai losses. For example, Maiek’s futuie The genetic approach will disease impairs the birds’ probably have limited success, mechanism for resistance to but should be tried At present, other disease. Therefore, buds it is the only method that has haiboring Marek’s disease aie pioved fruitful The thud ap more susceptible to othei mfec- pioach is that of piophylaxis 01 tions agents, coccidiosis being therapy with dings So far all foremost This could explain why attempts to attack virus diseases coccidiosis is often associated and cancer with dings have been with Maiek’s disease But which extiemely disappointing How comes first 9 Dr Maag believes evei. as scientific knowledge in itial Maiek’s disease induces the oeases, joint effoits of chemists occunence of clinical coccidiosis and biologists may one day be and not vice veisa Coccidiosis icwaided |Red Rose ■ DAIRY FEEDS On pasture ... and in the barn ... your cows NEED MINERALS! THESE DEALERS CAN SERVE YOU WITH YOUR NEEDS j Walter Binkley & Son Brown & Rea, Inc. Elverson Supply Co. Elverson Henry E. Garber R. D. 1, Elizabethtown, Pa. L. T. Ge»b Estate Manheim I. B. Graybilf & Son Refton Strasburg Review m 2 fuluie methods to contiol Mmck's disease, three # Red Rose Free-Choice Mineral is recommended where there is heavy use of corn silage* Red Rose Super Miheral is designed for dairy herds where legume roughage is fed. Be sure include Red Rose Minerals in your feeding program. Lititz Atglen Pin due aaionom.M Staiilm \ p.,.i liei says that Com Hell faim eis can apply potassium and phosphoius at times other than plant mu and still depend on high yield* In the \ugust September (1969) issue of Crops and Soils Magazine. Baiber tepoits on a sixteen-year experiment at the Pm due Agronomy Faim, where both broadcast and row applica tions of phosphoius and potas sium were studied In both the i ow and broadcast applications of phosphoius. corn yields the fourth year after ap hcation vveie almost as high as yields the yeai the fertilizer was applied Thus potassium could be applied on the test soil at any convenient time and still be used eFectnely Bioadcast applications of phos phoius vveie moie effective in pioducing high corn yields than weie row applications alone. Phosphoius applied b\ the low FEED YOUR COWS the best your know how! Red Rose Dairy Feeds . . . and Red Rose Supplements . . , are the feeds you need! They provide all the nutrients cows need for maintenance and put more milk in the pail. Take Red Rose 14 Test-Cow Feed, for example. This course-textured all purpose feed can be fed to your milk ing cows, dry cows, calves and bulls. You can feed it all seasons but it's especially helpful to keep appetites from lagging during warm weather. . | Other Red Rose Dairy Feeds are available in many protein’ levels. Select the one that suits your particular need and feed with a satisfaction you have never known before! J E. Musser Heisey & Son R. D.-#2, Mt. Joy, Pa. Heistand Bros. Elizabethtown Red Rose Form Service, Inc. N. Church St., Quarryvilie David 6. Hurst BowmansviHe Martin's Feed Mill; Inc. * R. D. 3, Ephrata, Pa. Mountville Feed Service Mountville Purdue Agronomist' Reports Experiment m itici fw-ctl corn yields ton bushel? .11*. .u io Wheie phosphorus was hio.idun and plow<sQvjjndetv yields wcie as much as iftte’bush els hmher than the best yield? bom iow application of eqmva lent amounts. Bioadcast applications woikod well with potassium, also, but the Pm due researchers found potassium less flexible than phos phorus There was greater fixa tion by the soil and greater re moval by the crop A single po tassium application was found to be relatively effective for two years. This means that there iy still flexibility in the time of ap plication. even though the resi dual effects of potassium are not as great as those for phos phorus Many farmers are already us mg this system of fertilization with excellent results, and though it may not work foi all soils. Barber believes it applies to a large poition of the Corn Belt. \t the lates of fertilizer used today, he says, phosphoius and potassium can be appl.ed mainly as bioadcast applications. Musser Forms, fnc. Columbia Musser's Mil! The Buck Chas. E. Saucier & Sons Terre Hill Ammon E. Shelly Lititz E, P. Sports, Inc. Honey Brook H, M. Stauffer & Sons, , Inc. Witmer
Significant historical Pennsylvania newspapers