2 I TUESDAY, Nov. 2, 2010 NEWS IN BRIEF Blood dfi►e challenge begins The 17th annual Penn State-Michigan State blood donor challenge began Monday, Nov. 1 and will continue through Nov. 18. Penn State has beat Michigan State four years in a row and eleven times in total. The goal is to receive 2,000 units of blood in the next three weeks, Red Cross club member Jordan Thomas (junior-meteorology) said. Every blood donor receives a free T-shirt and is entered into a raffle to win a prize, such as a flat screen TV or $2OO shopping spree. Blood donor Steve Koller said he donated blood because some of his family members have needed blood in the past. "I just know that some people need it more than I do," Koller (junior-sociology) said. "I've seen first hand what my blood can do to help other people." All blood drive locations for the contest can be found online at http://psuredcross.org. Jerzy Lewandowski, of the University of Warsaw (Poland), will talk about "The Possible Partition Fbnctions for the Engle-Pereira-Rovelli-Livine (EPRL) Model," today at 10 a.m. in 320 Whitmore Laboratory. Penn State professor Gregory Larsen will talk about "Simulated Adsorption and Characterization of Novel Nanoporous Polymers," today at 10:00 a.m. in 301 Steidle Building. Mark Dykman, of Michigan State University, will speak about "Fluctuation-Induced Switching and Power Spectra of Modulated Quantum Oscillators," today at 3:30 p.m. in 339 Davey Laboratory. LUNCH Findlay, Pollock, Redifer and Warnock: Minestrone soup, tor tilla and corn soup, bbq chicken bacon pizza, cheese pizza, chicken and broccoli stir fry, Jamaican jerk chicken pizza, potato and cheese pierogies, sauteed onions, sour cream, sticky rice, kyoto blend, peas, shoestring fries Simmons: Baked tomato basil tofu, tuscan smoked turkey wrap, bruschetta flatbread pizza, whole wheat cajun chicken flatbread pizza, whole wheat, milano sauce, turkey sausage and pepper heroes, whole wheat penne with asparagus red pepper, baked sweet potato, broccoli florettes, green beans and sunflower seeds, Israeli couscous and mushroom pilaf, jasmine rice with edamame, primavera vegetables, roasted roma tomatoes Waring: Chili con carne, lunch roll basket, broccoli florettes, but tered corn, chicken and biscuits, chicken cosmo not, feature burger, feature grilled chicken sandwich, grilled chicken breast, quarter pound hamburger, shoestring fries, teriyaki beef stir fry, baked potato, broccoli florettes, brown rice and grain pilaf, cheese sauce, tortilla and corn soup, vegetarian burger DINNER Findlay, Pollock, Redifer and Warnock: Minestrone soup, tor tilla and corn soup, alfredo sauce, chicken alfredo fettuccini, grilled chicken breast, miso glazed white fish, sour cream, zuc chini corn quesadilla, Italian green beans, kyoto blend, orzo risotto Simmons: Fresh fish cajun style, chicken polo a la vino, garden quesadilla, grilled chicken breast, linguini, roasted tomato sauce, baked sweet potato, broccoli florettes, green beans and sunflower seeds, Israeli couscous and mushroom pilaf, jasmine rice with edamame, primavera vegetables Waring: Chili con came, lunch roll basket, broccoli florettes, but tered corn, chicken and biscuits, chicken cosmo not, feature burger, feature grilled chicken sandwich, grilled chicken breast, quarter pound hamburger, shoestring fries, teriyaki beef stir fry, baked potato, broccoli florettes, brown rice and grain pilaf, cheese sauce, tortilla and corn soup, vegetarian burger, ken tucky bbq turkey sandwich, texas style baked beans Corrections: An extracted quote with an article "PSU bans logo from shot glasses" on page 1 of Monday's Daily Collegian incorrectly identified an individual. The person quoted was student Hunter Smith. 10 Follow us on Twitter for up-to-the-moment news www.twitter.com/dailycollegian Collegian Collegian Inc James Building, 123 S. Burrowes St., State College, PA 16801-3882 The Daily Collegian Online, which can be found at www.psucolleglan.com, is updat ed daily with the information published in the print edition. It also contains expand ed coverage, longer versions of some stories and letters, Web-only features and pre vious stories from our archives. Our site features full News and Business division list ings and e-mail addresses. News Division News, Opinions, Arts and Entertainment, Sports. Photo. Graphics, The Daily Collegian Online and The Weekly Collegian Phone: (814) 865-1828 ■ noon to midnight Sunday; 10 a.m. to midnight Monday to Thursday Business Division Advertising, circulation, accounting and classifieds Phone: (814) 865-2531 Fax: (814) 865-3848 ■ 8 a.m. to 5 p.m. weekdays Editor In Chief Managing Editor .... 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On the World Wide Web Fax: (814) 863-1126 Board of Editors Boon] of Managers Kelsey Thompson Chase Vickery .Tom DePinto, Hank Sherwood Alissa•Nemzer Sara Chroman, Ben Gasbarre Stephanie Haas .Anna Chau Danielle Meyers Jamie Leder LOCAL & NATION Tonight: Extended forecast NVelther - Today: C) Tomorrow: campumeathersarvlca.coin tt High 52 Low 28 * 0 High 49 Courtesy of Campus Weather Service Brain energy crisis may spark Parkinson's WASHINGTON Parkinson's disease may stem from an energy crisis in the brain, years before symptoms appear. If the research pans out, it points to a possible new approach for Parkinson's: Giving a boost to a key power switch inside brain cells in hopes of slowing the disease's inevitable march instead of just treating symptoms. "This is an extremely important and interesting observation that opens up new therapeutic targets," says Dr. Flint Beal of New York's Weill Cornell Medical College, who wasn't involved with the new study. Beal said scientists already are planning first-stage tests to see if a drug now used for diabetes might help Parkinson's, too, by targeting one of the implicated energy genes. At issue are little power factories inside cells, called mitochondria. Increasingly, scientists suspect that malfunctioning mitochondria play some role in a list of degener ative brain diseases. After all, brain cells are energy hogs, making up about 2 percent of body weight yet consuming about 20 percent of the body's energy. So a power drain could trigger some serious long-term consequences. "It could be a root cause" of Parkinson's, says Dr. Clemens Scherzer of Boston's Brigham and Women's Hospital and Harvard University. About 5 million people world wide, and 1.5 million in the U.S., have Parkinson's, characterized by increasingly severe tremors and periodically stiff or frozen limbs. Patients gradually lose brain cells that produce dopamine, a chemical key to the circuitry that controls muscle movement. There is no cure, although First lady rallies Pa. Democrats on election's eve PHILADELPHIA More than a thousand people packed into a chilly University of Pennsylvania quadrangle Monday night to hear first lady Michelle Obama tell them that sitting out this midterm elec tion could stop progress for people struggling to stay in the middle class, afford college or get health care. Obama spoke on the eve of today's election, in which Pennsylvanians will select among candidates for U.S. senator, gover nor and the state's 19 congression al seats. With Pennsylvania's Democratic candidates trailing in polls for gov ernor and U.S. Senate, Obama said digging out of the recession's depths is difficult and President Barack Obama needs strong lead- Election From Page 1 Bard (sophomore-political science and economics) said. He said com mittee members would stick around after the polls close to watch the results in the HUB and hand out any leftover food from earlier in the day. Members of the Penn State College Republicans will work the polling location in the Paul Robeson Cultural Center's Heritage Hall up until polls close at 8 p.m., Vice Chairman Anthony Christina said. psuc.llegian.com highest royalty revenue in the logo on a shot glass sends a mes nation's from the Collegiate sage the university does not con- Licensing Company, according to done. the company's rankings for the The decision has elicited a mixed swoman. Many universities ban 2009-2010 fiscal year. reaction from students and corn their logo not only on shot glasses, Purves said the company can't munity members. but also wine glasses, flasks and release how much revenue the uni- Shot glasses will be phased out other alcohol containers, she said. versity is projected to lose by opt- of stores, Rushton said and the Some universities have restric- ing to no longer license its name or licensing company has been told to tions on incendiary devices as well, logo on shot glasses. deny requests for the university's like firearms and lighters, Powers University spokesman Geoff logo or names on shot glasses. said. Rushton said the decision was Sales From Page 1 Penn State receives the ninth made because having the name or To e-mail reporter: mers2oo@psu.edu Elizabeth Murphy Alex Weisler Beth Ann Downey Council Andrew Metcalf Lexi Belculfine Chris Zook From Page 1 Somer Wiggins Council member Peter Morris said he thought the developer's propos al was "quite reasonable," consid ering that many of the buildings in downtown State College have high er levels of stories. Kevin Cirilli Ashley Gold Laura Nichols La une Stern Steve Hennessey However, the building would sit next to a neighborhood where many community members live. Ever since the issue was first intro duced, many State College resi dents have attended borough coun cil meetings to express their con cern that another apartment build ing would bring too many students to an already unstable area of State College. Lafer stressed the importance of listening to such community mem bers. Paul Casella Nate Mink "When people who live in the Lauren Neergaard ASSOCIATED PRESS By Marc Levy ASSOCIATED PRESS "This is an extremely important and interesting observation that opens up new therapeutic targets." dopamine-boosting medication and an implanted device called deep brain stimulation can help some symptoms. No one knows what causes Parkinson's. To find genetic clues, Scherzer gathered an international team of researchers to comb stud ies of more than 300 samples of brain tissue from diagnosed Parkinson's patients, from symp tom-free people whose brains showed early Parkinson's damage was brewing, and from people whose brains appeared normal. They even used a laser beam to cut out individual dopamine-producing neurons in the most ravaged brain region, the substantia nigra, and examine gene activity. The team found 10 sets of genes that work at abnormally low levels in Parkinson's patients, genes that turned out to play various roles in the mitochondria's energy produc tion, Scherzer recently reported in the journal Science Translational Medicine. Especially compelling, the genes also were sluggish in people with pre symptomatic, simmering Parkinson's. And all the gene sets are con trolled by what Scherzer calls a master regulator gene named PGC-lalpha responsible for acti vating many other genes that maintain and repair those mito chondrial power factories. So might revving up PGC-lalpha in turn boost underperforming mitochondrial genes and protect the brain? To see, the researchers ers by him through the fear, cyni cism and doubt. "As Americans, we have always pushed past the cynicism, we have always kept moving forward," Michelle Obama said. "And you know what? That is what we must do again today because there's too much at stake. There's too much at stake, and we have come much too far to turn back now.., Pennsylvania's top elected Democrats, outgoing Gov. Ed Rendell and Sen. Bob Casey, also spoke, as did Democratic guberna torial candidate Dan Onorato and the party's nominee for U.S. Senate, Joe Sestak. Specifically, Obama talked about new laws signed by her husband that expand college tuition aid to students by diverting money that once went to banks to provide fed eral loans, prevent health insurers "I hope they realize that this election cycle is going to be key for the next couple of years." Christina (sophomore-political tion in the elections is the best way science and history) said he for students to have a direct impact expects a big rush around noon in what happens in government. and is optimistic about the overall think students are becoming turnout. more aware of issues that matter Bard said he hopes these efforts most," Bard said. "I hope they real will encourage students to get ize that this election cycle is going involved and vote in the election. to be key for the next couple of There is a chance to break the years." turnout record from the 2006 midterms, he said, and participa- To e-mail reporter: kmws34o@psu.edu "That kind of business draws people downtown," he said. People aren't hanging out in front of the Palmerton." West End came to us last year, we listened," she said. "I think we have to take strongly into account that the neighbors do not want a building higher than four or five stories." Council member Ron Filippelli pointed to student behavior prob lems, describing the image of drunken students outside of Canyon Pizza. Ignoring the current problems in the Beaver Canyon area, including the cost of police services, he said, is not a solution. "Because Beaver Canyon is a THE DAILY COLLEGIAN Dr. Sint Beal New York's Weill Cornell Medical College tested dopamine-producing neu rons from rats that were treated in ways known to cause Parkinson's like damage. Sure enough, boost ing the power switch prevented that damage. This genetic evidence supports years of tantalizing hints that mito chondria are culprits in Parkinson's, says Dr. Timothy Greenamyre of the University of Pittsburgh Medical Center. He ticks off the clues: A rare, inherited form of Parkinson's is caused by a mutated gene involved with mitochondrial function. A pes ticide named rotenone that can kill dopamine cells and trigger Parkinson's symptoms in animals also is toxic to mitochondria. So is another Parkinson's-triggering chemical named MPTP Now with Scherzer's study, "it's going to be harder and harder for people to think that mitochondria are just a late player or an inciden tal player in Parkinson's disease," Greenamyre says. The crux of all that complicated neurogenetics: A diabetes drug named Actos is among the com pounds known to activate part of that PGC-lalpha pathway, and Weill Cornell's Beal says it's poised for an initial small trial in Parkinson's. Separately, a nutrient named Coenzyme QlO is believed impor tant in mitochondrial energy pro duction, and Beal is leading a study to see if high doses might help Parkinson's. Results are due in 2012. from disqualifying sick people from coverage and cut taxes for the mid dle class. In moderate Pennsylvania, which has 8.4 million registered voters. Democrats have a substan tial registration advantage over Republicans of 1.2 million, thanks in part to a surge two years ago in support of Barack Obama's presi dential candidacy from younger voters and minorities. But Democrats are trying might ily to get those voters interested in the election and into voting booths to counter what pollsters say is widespread discontent with job lessness and a strong Republican reaction to the Obama administra tion's policies. On Monday morn ing, Republican U.S. Senate candi date Pat Toomey addressed a GOP rally in northeast Philadelphia, lay ing out his argument for GOP con trol of Congress. UPUA Governmental Affairs committee chairman mess anyway, so let's increase it to me that's not a very good argu ment," he said. State College resident James Meashey said that rezoning might solve some of these problems. By removing businesses like Canyon Pizza, he said, there would be less of a cause for people to con gregate downtown. "That kind of business draws people downtown," he said. "People aren't hanging out in front of the Palmerton." To e-mail reporter cabs3s6@psu.edu Ti Bard James Meashey State College resident