BtTSINESS CARDS SAMII4L :0; - IVINCIARD, ATTOILNICV AT LAW, Itrosausumi, berm. , 4171,07P1a5, No. 69 GRANT street, between ninth street nd Trlspond alley. ap6 J - AM ES A. LOIVRIE, Attorney at Law, cr office Fourth street, Pill...burgh, between Smitlifield and Cherry alloy. decthly AIIL, Surgeon Dentist, successor to 0. W.131d31e, No. 144 Smithfield street. Aar Office !ware from 8 to 1 o'clock, aud from 2 to tablfely u,SCOTT, Dentist, Fourth street, five doors . woej of Markel. 44 - Office hours from 1) o'clock A. M. to It o'cloch 2. M. docny SCIIOONMAKER, Manufacturer ,of . . • White Lead, Red Lead, Zinc, Paint, Lithargo,Putty, Ste.; Wlsolesa to dealer in Oils, Paints, Varnishes, Ttupentine, .te.o No. 24, V, and street, Pittsburgh.y-'22 JOSEPH FLEMING, successor to L. Wil oox & co, corner of Maiket street and the Diamond, keeps constantly on hand a full assortment of DRUGS, MED. 101. NE, MEDICINE CIiESTS, PERFUMERY, and all arti• cies pertaining to his business.. 41a" Physicians' Prescriptions carefully compounded at all Lioll.ll. Je9:y T . W. CHADWICK, dealer in Kentucky Leaf TOBACCO, RAGS and PAPER., No. 149 Wood street, below Sixth, Pittsburgh. taPV:IY *3l/`The highest market price, in cash, paid for Raga. WALTII4 i'. bIIII.4I.IALLL JOSMI a. LIUGUE . WP. MARSHALL & Co., Importers and • dealers in French and American PAPER RANO. LllOB, No. 87 Wood street, Pittsburgh. Air Ste e agents for the celebrated numufactures of Messrs. Dellocrart . Co.,Paris. ang7 DAfiD CAMPBELL & SAMUEL POL LOCK have associated together ut.der the style of thittilitiLL b. POLLOCK, for the transaction of a general Variety and DrY - Goods business, and the manufacture of plain and 'sued Line Gilt lion Wings. mhl9 PHILIP ILEVAL 11011i111' I. dNDRIIBO3 &„- AN DERSON, (successors to Joalota 2thodeo & C 0.,; wholesale dealers in FOREIGN FRUITS, NUTS, SPICES, CON'ECTIONARY, SUGARS, &c., No. 39 Wood strut, appoint. the St. Charles Hotel, Pitts. burgh. np:d a. J. OILLYSPIi JJ. GILLESPIE & CO, Looking ism Alauntactarers, • and dealers iu Looking Glass I'l Itlate Glass, hu gravings, Combs and Fancy Goods, N 0.70 Wood street, Pitts btirgh. cOn hand and made to order, Gilt Pier as , Mantle Glasses, Mahogany, Rosewood, Walnut and Gilt if, dales, or lig, of every description. AFir Steamboat Cabins itocorat, Cor zedicinal punKe__ at - Pa* nalllNS'es Winter Arrangement. ON AND AFTER MONDAY, JAN. 18. PENNSYLVANIA CENTRAL RAILROAD E 1 V E ID .4, II IL THE FAS r MALL =LAIN inavos the Possunzer tion ovary. morning, o:stlept &Oa o'clock, Pittaba.zh limo, arriving to t'hilaellpiiia at 11=0 P.,IL 'DAB kik_ertit6a TitAL.‘ lcaves the litation every evening at woo o'cltwk. Stopping tally at tiroonabrirg, Latrobei Johnis. town, Willtuora, tiatuthiu Altoona, &c., connecting at Bar rilburg witt, th. Xrtuu Odom tor Baltimore, and arriving in putlaoolphin or tialtunura at .00U o'clock, P. Al. AIAJOSIIIuDATILLN TILA.LNS THE JOlllizToWzi avY:UMMOLe'IiUN TRAIN lesVos dory (except oarida,v,) at 3:ku o'clock, P. M. otopping ut au otationo, awl running as Lai as Coneraaugh. AOtluaLlivLAT/UN TRAIN for 'turtle Oreek Bridge leaves daily, (except linnday„) at 10:40, A. M. ziWUND AGULLUMuIIATILLN TRAIN for Turtle °reek, Leave,' daily, (except Ounday,) at 4-'43 P. U. UMW AUQUALII.O.I)AIIuN MASA for Turtle Greek, loavea.daily, (except ourlay,) at tr.xe, P. U. Ultiv 'ISIS Tits I NS arrive in Pittsburgh as tollows Express, P. M.; Mail, 6.00 A. al.; Johnstown Accommo• dation, 11:50 A. U.; hares turtle Creek. Acuumniodaticity &SO, A. 31., 6ticuucl ACCOILLLUOWAVIOtt, 12.:40, P. al.; Third Accom modation, oat), r. M. Trwae iur Blain - Ville and Lathan., connect at Biairevilu lutorsoalou it.h Wail tram hnst, Layroas Halm want, and ttku Johnstown aiscomodatton train taut and West. Yr.V.I:bISUE.UII. AND CAJANINELLSVILLE IHALN b, stopping at all citattous on the Yttiauurgli and Gentians vile Lead, leave daily; (Sunday bECeptc4,) as follOws: MAIL I'HAIN, 7.0 u A. 15.1. m...X.L'iLtb6 111. A IN, 4.ZU Y. M. 11..NaUtl:111 , 41.1111A.11 , 18 Irocu Yittaburgh and Jouuellsville head, arrive at ntusbargh, 11.00aA. 11. ,u,auau r. u. id!. The travellug paullc will mai . it greatly to their in• Wrest, in gunig klaat ur to cravat by tau t'enuny.vania Railroad, an We accommodations now aka - v.l eacuaut our panned on any other route. de tun Rua& u baLlanted with dt.utio, and to uuLuely Inau drat, we can procaine dainty, speed and cuuuut t to ad atm may 1w:or thin a.uad with their patronage. k SAE I . . to new York—. " Yluludolphial Baggage checited to ail btatiOnToii the Pennsylvania ltuil roau, anti to Philadelphia, Baltimore and New York. • Paseengera purrhaqing tic/tete ni cars, win be cuarged ten could in addition to tho Otatiou .rates, except Irma 001010115 Where , the elluipany had no Agent. NUMCB.—in Cade of liatie, tun Company . will hold them aeleee reeponnible for personal' baggage only, and fur an amount nut exceeding $lOO. n.—/:he Bxcelslor thin:alma Line ben been employed to convey Ifussnuprel and Baggage to mid Isom the Delay et a charge nut to exceed 46 ceuta for each paaaonger and bag gage. ;or tickets apply to J. STEWART, Agent, At the P. it. it. Passenger btatluLlp on Liberty and tirant streets. TILE PENNSILLViNLI. RAILROAD. , TUE GitEAT itt.PUILF,,, connecting the Atlantic Cities with Western . North-western atm Noma-western States byp continuous Railway direct. This Road alto connects at Pittsburgh with U. i 01 Steamers to all ports on the Wee at Clove laud and Sandusky with steamers to all ports ou the North western Lakes; making the most DIRSOT, onsarasi and IiBLE nom by which PitkiltlLLT can be :or - warded to and (ruin the lialt.2 WEST. Rates between Philadelphia Cc I FIRST CLASS.—Boots, Shoes, Hats and" Caps, Books, Dry Hoods, (in boxes, bales and trunks,) Drugs, (in boxesautl bales) ' Feathers, Furs, Ito. SECOND CLASS—Domestic Sheeting, Suitt mg and Ticking (in original uales), Drugs (in casks), Hardware. Leather (in rollaor boxes), Wool, and Snoop Pelts, Eastward, Ac., Ac. TlllitD CLASS.—Anvils, Steel, Chains (in' casks), Hemp, Bacon and Pork, Salted (loose or in sacks), Tobacco, marmite> tared, (except Cigar s or cut,) Ac., Ac. FOUR'I'IIIJLAhB--I.lotleta, Fish, Bacon, Beef and Pork, (in casks or boxes Eastward,) Lard and Lard Oil, N ads, Soda Ash, Her man Clay, Tar, Pitch, Beam " At, Ac. FLOUII--$l,OO %,l bbL until further notice , GRAIN in car loads, 45 cts. 100 Iba. until further notice. COTTON—S 2 Vi bale, not exceeding boo tbs. wenpat, maul further notice. ,rryz- In shipping Goods from any point East of Philadel pirm, be particular to mark packages "vat Pennsylvama AcatmuL" All Goods consignedto the Agents of this Road at Philadelphia or Pittsburgh, will be forwarded without deteuilute. Nassau Jamas—Harris, Wormley A Co, Memphis, Tenn.; R. F. Sass A Co ' St. Louis} e. 4- u'itiloy Co., Evansville, Ind.; Dumesnil,Boll and Carter A Jewett, Louisville, Ky.; IL C. Meldrum, Madison, Ind ; H. W. Brown Co. anti Irwin Co., Cincinnati; N. W. Hrsham A Co., Zi , neaville, Ohio; Leech A Co, No. 54 Kilby street, Boston; Leech A Co, No. 2 Astor House, New York ; No.l William street, and No. Battery Piece, New York ; ,E, J. Sneeder, Philadelphia; Ilagraw s Koons. Italian:tine; D. A. Stewart, Pittsburgh. H. IL HOUSTON, General Freight Agent. 11. J. LOMBAERT, myl Superintendent, Altoorm, Pa. 9:4q A. Az P 7:30 e. N. 3:46 P. m 9:00 P.M PITTSBURGH it, CONNELLSVILI.E B.AIL Tag Pittsburgh and Connellstrille Railroad is now openee fur thp transportation of passongera and freight to and from Pittsburgh and Commßoyale, connecting with the Peuusyl vania Central Railroad at Erinton'e Station. Arrangements have also been made with the Pennsylvania Central Railroad, by which thrtiugh freight to Philadelphia and Baltimore will be carried from points on the Pittsburgh and Connellsvilleßailroad, by car loads, on favorable terms. RUNNING OF TRAINS.—On and after Monday, •28th of December, the Passenger Trains will be run daily, except Sundays, as hallows: MAIL TRAIN, will leave the Passenger Station of the Pennsylvania Railroad, at Pittsburgh, at 7:00 o'clock, A. M., arriving at Connellsville at MOO A M. 11.XPRE88 PASSRNOLIt TRAIN, leaving Pittsburgh at 4:20 o'clock, P. M.., and arriving at Connellsville at 8:20 P. M. RETURNING,—EXPRESS TRA.L'i will leave Comic villa at 6 o'clock, A. NI, connecting with the Bhuraville Accommodation Train, on the Pennsylvania Railroad which arrivea at Pittsburgh at 11 A. M. MAIL TRAIN, leaving Cannel to, die at 2:00 P. 81., and connects with the Brintou Accommodation Train, on the Pennsylvania Railroad, which arrives in Pittsburgh at 6.00 c. M. Freight to and from Pittsburgh, and stations on the Pitts burgh and Counellsvillo Road, nill be received and delivered at Baldwin Depot! opposite Duquesne Depot, on Liberty street. Bunting & Hall's Coaches for Mt. Pleasant, Uniontown, Frostburg, Cumberland, will leave Connellsville regularly on the arrival of the trains. Mail Train connects also at West Newton with coaches, by the Plank Road, wilh Mount Pleasant, Ron:corset, Berlin, Sandpatch, Cumberland, eto Tickets can 00 had from Ticket Agent at the Pennsylvania Railroad Passenger Depot. mrl6 IL BLACKSTONE, Superintendent. Joseph WhitWe Carriage aapository. TOSEPH WHITE, now carrying on bumf- mesa in his spacious premises, (pow lately, »..f.,..(44;* . enlarged,) on the Pittsburgh and Greensburg Turnpike, near the Two Mile Run, between Pittsburgh and Lawrenseville, respectfully Invites the public to'inspect his atoUr• of CARRIAGES, BUGGIES, Co. And he particularly informs gentlemen purchasers, that one price only is made. Fourteen years' experience in the business enables him to place before his patrons the same choice collection of elr• riagos which, so many years past it has boon his particular department to select, from the various and most talented Eastern manufacturers. The success of his new system is complete—the economy of his arrangements will supply the best and most fashionable manufactures at moderate prices. Unencumbered by those heavy expenses, which the mania for decorating houses of business has heaped upon the price of goods, (owing to large rents, JOSEPH WHITE will sell, on ready money only, at ranch less than the usual prices. ii&„..Carriages repaired in the best manner with despatch untayl2dsw pOTATOES.- LW bus. Neshannock Potatoes; 60 du Peach Blossom Potatoes, just received, and for sa:e by JAMES A. BETZBR, RS Vats.? etrort, RYE FLOUR.- 16 bbla. fresh ground Ryo Flour, Just received and for sale by JAMS A. FETZER, Janl 89 Water street. ,GREEN APPLES.- 20 bble. gre'eu apples, - Just received and for sale by ocr2o JAIL A. FETZER, 89 Water street. QWEET POTATOES. 10 40 bush. Street Potatoes, Just received and for sale cc= JAB. A. BETZEF, 89 Water street. APPLES.- 29 bble. extra fine Rambo and Belieflower; 88 ." - Vandiver, 100 " Rumen Apples, Just reed and for sale by dell JAS. A. lIRTZFaI, 89 Water street. ~u' '`~` FLOUR. 100 bbla. choice Extra Superfine; 60 " " Superfine Flour, fast receive, and for sale by JAMES A. FETZER, dent 89 Water street DLANK ACCOUNT BOOKS.—A large stock of every description, in store and for Bale by W. S. RAVEN, Corner of Market and Second streets CIDER.-10 Barrels Sweet Cider, for sale by JAMES A. FETZER, decl 89 Water street INDIA RUBBER INKSTANDS- Another lot of those airtight INKS, just received arid for r de by W. S. HAVEN, or :TO Carter Harks: and Second attracts. DUFF AND FLEMING'S Book-Keeping for gale at W. S. HAVEN'S, Stationery Warehouse, Corner Market and Second streets. TRNVE.LOPE - B. Buff, Blue aut ~ into Laid, Adhesive, Cloth Lined and Parchment Paper V ez t ra thick Cream braid do.; Legal do.; Note do.; all alma; for sale by W. S. H kVEN, octal • - -Comer fdarketand Second eta. rIASKET, Binders, Straw, Bonnet, and Njißeen Board, for sale by W. S. HAVEN, Nce. 81, 33 and 35, Corner s.l.izi.et and Second street]. T — EAS.-30 half chests Young Hyson, Im perial, Gunpowder, Black Tea.... in etoro and for sal,. JAM.I-3' PATTON, Jr., Allegheny City. WEST INDIA PRESERVES. —lO dozen assorted, just reoeivetl and for sale by ANDERSON, daR No. 80 Wood atrodt ELLIES.--50idozen Ourrtait; - Blackbery Qv Orange, Quince, Peach, arid Grape Jelhes;for sale by ILEYlilFdl, 3 ANDERSON, 303 89 Wool street, opposite St Marls, ties prime Rice, just receiv ed and for sale by NLILLEIt le ItICKETSON, rola?. No 221 and 223 Liberty street- fiIIEESE-40,boxes prime Western Res' °rye %a for wile by I da.211 WM. B. BMEMI t CO. VILIZABETHAN.—A new Decorative Wall jua Paper, Elizabethan design, just received, and for sale. by W. P. kIAP.SHALL C 0.,& 87 Wood Stlw.t. FLOUR. -2,5 bble. Superfine Flour received fiat' for eale by McCANDLEA DIEANB & le2o Corner Wood and Water street& - LIMITS for Christmas and New Year.— .8: Best Layer Raisins; choice new Figs, In drums and pa per boxes, only Hain. Vb., at HA W~BTu , BRO. &BB )WNLEE'S, o. tie Diemced. ('TORN SHE TABS.—Smith's Patent, ar la =gad for hand, horn or steam power, warranted in every Tweet, and will shell tram 30 to 40 bnahele. of corn per Um. Will be aold towrhy CVO_ _ .• • • • Wain EL GOWAN% RAILROADS. T.L.l,tniTo I. 3 altimuru its uu " Luzic.a.uvr. kleti I nsuarg, F. 40, . . H 8 0 A D . '`, DOCTOR HOOFLAND'S CELEBRATED GERIIIAN HITTERS, P 55 1 ,554 5 . es Da. 0. M: JACKSON, Primal:o'4PS, • ' Will effectually cura• WWI COMPLAINT, DYSPEPSIA JAUNDICE,' CHIIO. NIO OR. NERVOUS DEBILITY, DUTRA RES OP THE KIDNEYS, And ail Dirscues dritingifrom a sisters . -red goer yr "4"14 Such av Constlpa -I:km7l:mend Piles, Fullness, or Blcud to the Read, Acidity of the Stomach, th tte e r S in to g n at th h, o B P our it ° Ern i th c e ia B - to- Nauseati, Heartburn, Disgust fez Peed, fati lul ons, lneas sin eLw z oi , g o h r t v i i n u mach, Swimming of the - Head, flurried and Dallcalt Breathing, Fluttering , at the Heart, Choking or Suffocating sensations when in a lying posture,Dimness of. Visie • Dots or Webs before the Sight, Fever and Dull Pain in the Head, Deficiency of Perspiration, Yell lowness of the. Skin and Limbs, Pain n the Side, Back, Cheat, Limbs, dc, Sudden Flushes of Heat burn., lug in the Flesh, Constant Imaginings of Lvil, and great Depression of In attributing such valuable properties to this remedy, no rash or unwarrantable assertion is mado,:but is simply stated a fact; proven undeniably and conclusively by the extre.m. dinary cures, and benefits derived from its use, under the di. reetion of its ill istrious originator,Dr. lioodand, among all classes of European society, and f rom the immense main of testimony, from all parts of the American continent, scam mutated during the last ton years, in the hands of the pres ent proprietor. The prevalence of diseases to which the German Bitters are adapted, it is with sorrow we say it, is al. most universal; indeed there is scarcely a family throughout the whole extent of our country in which there cannot be foiled among Its members that peculiar sallow and fangend appearance denoting a diseased Liver, or an emaciated and qtufering Dyspeptic. , Then of what immense importance'to this class of invalid that a certain and reliable remedy should be placed wital their reach; one in which no baneful or injurious drug on ten into its composition; a remedy on which the patient can rely with the utmost conildence and certainty, and be assured rom actual and tangible proofs that the article he is using featly possesses the virtues attributed to it. Such a remedy ea "HOOFLAND'S GERM AN BITTERS." Thousands o dollars have been expended in its manufacture and diffusion throughout all parts of this continent, and the proprietor feels the greatest satisfaction in stating that there is no state, county, or oven village, where the Medicine has been introduced, that there casein be found numbers willing testify to its virtues. It is used constantly in the practice of a large number u tke most prominent Physicians in the country, who has'. also added' their written testimony in evidence of its grunt virtues. In conclusion, then, we would respectfully ask of all those afflicted with any of the above diseases to give tie Bitters a trial, and rest assured it will never be regretted. In proof of the statements above made, all are invited read attentively the Almanac published annually by the pro prietor, for Farmers and Families, containing n great num ber of useful receipts, in addition to the testimony in levy,. of the hitters, from the most prominent and well known in dividuals in all parts of the Union. All Agents for the Bit ters are authortud to distribute the Almanac gratuitously. Principal (Mice and klanufactory,96 Arch street, Philadel phia, Pa. For sale wholesale by Druggists in ail the principal cities, and at retail by Apothecaries and Storekeepers in every town in the United States and Canada, and by B. L. VAIINESTOCR & CO. and Dr. GEO. H. KEYSER, Pittabargh. JY I2 4/Ydesw itts burgh Of all diseases the great, firdt cause Springs from neglect of Nature's lima SUFFER NOT WLIEN A CURE IS GUARANTEED IN all stages of SECRET DISEASES, Self-Abuse, Ner vous Debility, Strictures, Gloets, Gravel, Diabries, Diseases of the liddrieys and Bladder ' Mercurial Rheumatism, Seto- Pains in the Bones and Ankles, Diseases of the Lunge, Throat, Nose and Eyes, Ulcers upon the Bodyor Limbs, Can cers, Dropsy, Epileptic Fits, St. Vita's Dance, and all diseases arising from a derangement of the Sexual Organs, such as nervous trembling, loss of memory, hiss of power, general weakness, dimness of vision with peculiar spots appear in before the eyes, loss of sight, wakefulness, dyspepsia, liver diseases, eruptions upon the face, pain in the back and head, female irregularities and all improper discharges frem both sexes. It matters not from what cause the disease origins. ted, noweret, long standing or obstinate the case, recovery ib certain, and in a shorter time than a permanent cure can be effected by any other treatment, even after the disease has .baffled the skill of eminent physicians and resisted ail the r !means of cure. The medicines are pleasant without odor, causing no sickness and free from mercury or balsam. Dury ing twenty years of practice, I have rescued from the jaws of death many thousands, who, in the last stages of the above mentioned diseases had been given up to die by ands physicians, which warrants me in promising to the afflicted, who may place themselves under my care, a perfect and moat speedy cure. Secret diseases are the greatest enemies to health, as they are the first cause of Consumption, Fiero fulti and many other diseases, and should be a terror to the human family. As a permanent cure is scarcely ever effect-. ed, a majority of the cases falling into the hands of incone potent persons, who not only fail to cure the diseases halt ruin the constitution, filling the system with mercury, which, with the disease, hastens the sufferer Into a rapid Consumption. But should the disease and the treatment not cause death speedily, and the victim marries, the disease is entailed upon the children, who are born with feeble constitutions, and the current of life corrupted by a virus which betrays itself 411 Scrofula., Tatter, Ulcers, Eruptions and other affec. tiona of the skin, eyes, throat and lungs, entailing upon them a brief existence of suffering and consigning them to an early grave. SELF ABUSE is another formidable enemy to health, fri nothing else in the dread catalogue of human diseases causes so destructive a drain upon the system, drawing its thou sands of victims through a few years of suffering down to an untimely grass. It destroys the nervous system, rapidly wastes away the energies of life, causes mental derangement, prevents the proper development of the system, disqualifies tor marriage, society, business, and all earthly happiness, and leaves the sufferer wretched in body and mind, predis posed to Consumption and it train of evils more to be dreaded than death itself. With the fullest confidence as sure the unfortunate victims of Self-Abuse that a permanent and speedy care can be effected, and with the abandonment of ruinous practices my patients can be restored to robust, vigorous health. Tee afflicted are cautioned against the use of Patent Medi cates, for there are so many ingenious snares in the columns of the public prints to catch and rob the unwary suffelera that millions have their constitutions ruined by the vile compounds of quack doctors, or the equally poisonous nos trums vended as "Patent Medicines." I leave carefully ana lysed many of these called Patent Medicines and find that nearly all of them contain Corrosive Sublimate, which is one of the strongest preparations of mercury and a deadly poison, which instead of curing the disease disables the aye tem for life. 000. 11 100 Ms. 75c. ici 100 Ms. 65c. 41 100 10a 60c. "i 4 100 me Tiiree-fourths of the patent nostrums now in use are put up by unprincipled and ignorant persona, whodo not under stand even the alphabet of the inaterta medica, and are equal ly as destitute of any knowledge of the hunian system, hav ing one object only in view, and that to make money regard- less of consequences. Irregularities-and all &eases of males and females treated on principles established by twenty years of practice, and eanctioned by thousands of the most remarkable cures. Medicines, with full directions, sent to any . part of the United states or Canadas, by patients communicating their symptoms by letter. Business correspondence strictly con fidential. Address J. SUMALEIIVIT LE, 3L D., Office No. 1131 Filbert street, (Old No. 108,) below Twelfth, Philadelphia Private and Confidential Idedical Advice 1 AT TIIE BUFFALO PRIVATE ll.OSPl- TAL—Establishod for the cure of Syphilis, Seminal Weakness and the secret Infirmities of Youth and Maturity, by Dr. AMOS t 80N, Buffalo, N. Y. Office corner of Main and Quay streets, (up stairs.) A MOST nOIFIITHIO INVENTION. An instrument for the cure of Genital Debility, or Noctur nal Emissions, more properly known es Seminal Weakness, etc. Can be permanently cured in from fifteen to twenty daye, by the use of this instrument, when need conjointly with medicines. YOUNG lIIEN TARP PARTICULAR NOTICE. Dr. AMOS & SON take pleasure in announcing that they have invented a most important instrument for the cure et the above diseases. It has been subjected to a teat by the most eminent physicians in London. Paris, Philadelphia and New York; it has been declared the only useful instrument over yet invented, for the cure of Seminal Weakness,or any disease of the genital organs, yansed by the secret habits of youth. Dr. AMOS k SON, in order to satisfy the most skeptical as to the merits of their instrument, pledge themselves the! in any instance where they may prove unsatisfactory afte, fair trial, the money will be refunded by returning the in etrument In good order. Persons wishing the above useful Instrument will °beery, that the price, with the accompanying directions, securely packed and sent by express, is ten dollars. NEW REMEDIES, AND QUICK CURES. Dr. AMOS A SON may bo consulted from eight o'clock the morning until nine at night, in every stage and spill. tom of the Venereal Disease, Gonorrhcea, Gleets Secondar Symptoms, Seminal Weakness, Impotence and S trictures the Urethra, etc., with inviolable secresy. The tre.auneu, they adopt is the rearut of upward of thirty years' exteneiv, and successful practice in London. The most inveterat. cases of Venereal Diseases eradiated in eight or nine dips. and cases of a slight nature in two or three days, at a mod erate expense. The cure effected without confinement or hindrance from business; also, nodes and pains iu the bum, and limbs, effectually eradicated. A LAME WARRANTED. Dr. AMOS & SON have devoted their attention exclusive ly to this peculiar class of maladies, and the relief they have consequently been enabled to render to their fellow-creature fully testilied and greatfully acknowledged by COllVaien ceutpatienta and others daily arriving in town from all parts of the country, for the express purpose only of cons ultat.ch, while their exertions have bean crowned with tote most sig nal advantages; yet from what they have exprienced i - inquiring into the causes of these infectious complaint i (from their most simple condition to that of the most dan gerous and inveterated) they have always entertained the possibility of their prevention and removal, and likewise in variably found that the most horrible and mangnant forms of disease could almost-always be traced to ono of the foe lowing causes t—lgnorancs, neglect, or the ill effects of un skilled and improper treatment; therefore, Dr. &YIDS a SON have succeeded in discovering, In the selection of their remedies, a safe, effectual, and cautions course; omitting ail combination of remedies which bear an equivocal chartictin as well as those whose premature or injudicious application might be, productiv a : of-bad counquences m the hands of private individuals. In short, the ]audible end of their ro medics is the lessening of a great mass of human misery by the atleniation, relief and prevention of those grievous lie Motions that aro In reality the secret foe of life, and which, while they so extremely surround us, call aloud for our skill and interference for their extermination. COUNTRY INY,AISDB, d Whi, p min i n , in any part of the world may be succmsfull) treated by forwarding a correct detail of their case, with r remittance for medicines, its. Addreee Dr. AMOS b SON, corner Main and Quay stretts Buffalo. N. Y. jaZl:d&sily DARISIAN TOOTH PASTE, prepared under the auperrnion of Dr. Itunihen, Surgeon Den net, for Belo by JOS. VLSMING, kOTHER supply of Low & Son's superior London Toilet doaye received today, by JOB. FLEMING, fele Corner Diamond and Market otree•t. riIIIORN'S - EXTRACT OF COPAL BA AN 1.) SARSAPARILLA.—Anotner supply of tide celebl awe Lugliah remedy, jast received by JUS. fe9 Comer Diamond and 3.larket street. MINERAL WATERS.—BIue Lick, Bed ford and Congress Watera constantly on hand at JOSEPH FLE fe9 ' Corner Diamond and Market street. Ferrated Tinot. Bark and Elixir of P-4„,1 Bark, on band and for sale by dP2O A V!: 4;8147101f 4 0 • I_l OHS.—Dressed Hogs, jnst received and for ra!o by JAMES A. YETZER, RII Water irtrc.t TERFIIMERY—Of descriptions and prices, can be had at JOS, FLEMING'S, fele Corner Diamond and 'Aiarlita etc ea. ADIANOS TO RENT.—Two elegant Rose A.- wood 6, octave Pinuos, will be rented to private, inn: Ries only. Apply to JOHN H. MELLOR, fel3 82 Wood greet. EN N EDY' MEDICAL DISCOVERY io &denim band and for sale by Davie _ D. L. riII:HIM:Ku /cc° A YER'S CHERRY PECTORAL AND OATHALUTIOPEI tEroas dash on hand for Wu Int _ RAEIREATOOK QO. MEDICAL. f4Atti&riii::WAtel3k- 1 1 0 .4 7 .ZviA R. • - • "01-er44.WtW": •, . 4 3 ri ..4. .-;:i4jr.nt.:4A _ Ik.tE VD A D L'4lc V E I‘,l F LIVER UNiffek €111.t.0 beet Pre= -g-xtri•ANDsso Ithee They are not recon mended as Univerf , Cure-alls,. but simply f what their name pu norts. The VERMIFUGE ) "spelling Worms fro: the human system, h:I also been administers _with the most satisfactory results to various anima' subject to Worms The LIVER PILLS ) to. the cure of LIVER COM PLAINT) all BILIOUS DE RANGEMENTS ) SICK HEAD ACHE, &c. Purchasers will pleast. be particular to ask f( r. Dr. C. McLane's C::« - brated VERMIFIJGE I:IVER PILLS, Prepared v vi 2 ltter .4.. kt, .PROPRIETORS, Lurgh, Pa., and take other, as there are various other preparations now hefore the public-, pur portina to be Vermifutlz z.., and __ Liver ~.1 others, in comparisoa with, Dr. McLANE's, C or thless. Tht: GENUINE MCLASI; Verrnifuge and Lis Pills can now be had all respectable Dr ii P.l S cores. E Tvl IN G • 1 .700 D ST., P/TTSBURMs, P.l IVILANE'S VERMIFUGE AND LIVER PILLS.-75 gross on hand and for gala by B. L. FAIINESTOOK dr. CO. Corner Wood and Fourth Woad. DRIVATE DISEASES.-DR. BROWN':i MEDICAL and SURGICAL Offices, No. 60 SMITHFIELD Street, Pitts. • burgh, Pa. DR.-BROWN is au old citizen cf burgh, and has been in practice for the last twenty-five years. His business has • been confined mostly to Private and Sur. t 7rAi, gical Diseases. etted CITIZENS AND STRANGERS 4,-iz.ffr•e"/" . in need of a medical friend, should not '',l"j?!.; • fail to find out the sure place of relief. :,`-;t'er,,l . :•- • • The Doctor is a regular graduate, and • ";,%"•/ . 4 1 his experience in the treatment of a certain class of dither es is a sure guarantee to the sufferers of obtaintng permanent relief, by the use of his remedies and following his advice. DR. BROWN'S REMEDIES never fail to cure the worst form of Venereal Menses—ail Impurities and Scrofulous Affections. Also, all diseasoe arising from a hereditary taint, which manifests itself in the form of a tatter, psoriasis, and a great many forms of akin diseases, the origin of which the patient is entirely ignorant To persons BO afflicted, Dr. B. offers hopes of a sure and speedy rooorery. SEMINAL WEAKNESS. Dr. Brown's remedies for this alarming trouble, brought on often by that military habit of sensual gratification which the young and weak-minded often give way to, (to their own destruction) are the only reliable remedies known in this country—they are safe, and make a speedy restoratiou tsy health. RUEIIItATIBM Dr. Brown's remedies never fail to cure this painful dis ease in a few days—ho will warrant a cure. lie also tr,ati Piles, Gleet, Gonorrhoea, Stricture, Urethral Discharges, re male Weakness, Monthly Suppressions, Diseases of the Joints, Fistula in Ano, Nervous Allortions, Pain in'the Back and Kidneys, Irritation of the Bladder, together with all diseases of an impure origin. A letter describing the symptoms, containing a pa:, di. rooted to DIL BROWN, No. 50 Smithfield street, Pittsburgh, Pa., will be immediately answered. Medicine sent to any address, safely packed and secure from observation. Office and Private Rooms, No. 50 Smithfield street, Pius. burgh, Pa. mr2s IT IS NOT A DYE. It IN. S. A. Allen's World's Hair Restorer. (1 lIAIRED, BALD, or pereorts xvitl diseases of hair, or scalp, read the following and judge of the articles: Mrs. S. A. ALLEN'S zirLonALsAmrm, Or WORLD'S HAIR DRESSING, is essential to use with the RESTORER, and is the beet Flair Dressing for old ur young extant, being often efficacious in cases of hair fall. ing, &a, without the Restorer. REV. IL V. DEGAN, Editor Guide to Holiness. "We cat testify to its effects," &c. PRESIDENT J. H. EATON, L. L. D., Blurfreeaboro', Tem, "Notwithstanding irregular use, the falling off of hair ceased, and my gray locks restored to original color," &c. REV. S. B. MORLEY, Attleboro', Massachusetts. "it has changed the "Crown of Glory," belonging to old men, to the original hue of youth," ,tc. REV. M. TEACHER, (60 years of age,) Pitcher, Chenangu county Now York. "My hair hi now restored, it is nothing like a dye," &c. REV. D. T. WOOD.lilidffistown, Now York. "My own hair, and that of another of my family, has greatly thicken. ed, where almost bald," !Lc. REV. JAMES hicrlEV, Now York city, recommends it, ha REV. W. PORTE:US, Stanwich, Conn. "It has met my most sanguine expectations, &c. REV. J. P. GRISWOLD, Washington, N. H. "It is really efficacious in restoring the hair," %c. REV. G. M. SPRATT, Lowish:ugh, Pennsylvania. " W can and do cheerfully recommend &c. REV. J. P. TUSTIN, Charlestown, South Carolina. " The white hair has become obviated," &c. REV. ADIOS BLANCIIARD, Meriden, N. H. "We think very highly of your preparation," &c. REV. B. C. SMITH, Prattaburgh, N. Y. '" I was surprised to find my hair turn as when I was young," &c. REV. CI H. CLINK, Lewiston, Pennsylvania. "Ithaf stop. ped my hair falling and caused a new growth." REV. A. PRINK., Chatangne county, New York. "I ara satisfied and recommend it." REV D. MOMS, Croats River, New York. "It is the bast preparation extant." REV. WILLIAM. CITITER' , Editor Mother's Magazine, New York. "Recommends it." iffirWe might swell this list, but if not convinced, TRY IT. We export these preparations to Europe oven, inni are superseding all others there ea well as in the it It does 1w Era of Stain. Sold by all the principal whole• sale and retail merchants in the tlnited States, Cuba, or Canada DEPOT 355 BROOM STREET, N. Y. ) where address all letters and haplika. tr4fr Some dealers try to sell articles instead of this ca which they make more profit. Write to Depot for circular, terms, and Information. Genuine is signed, Yrs. S. A. Allen written in ink. Beware of counterfeits. isep3ie-o4lllimlaw MRS. ALLEN'S HAIR RESTORER.-A largo supply always on band and I:or sale by novl6 B. L. WAHNESTOCK di CO SABIL. FAHSESTOCK, No, "14 Wood street, Pittsburgh, ITAS JUST RECEIVED DIRECT FROM 11. ENGLAND 'WALDRON ,GRIFFIN'S :arciuniz CORN AND GRAIN SCYTHE, CORN HORS; PATENT AND COMMON ANVILS; STEEL Traps, very superior 'Drawer 'Locks, very superior Gun Locks, Tinned. and Enamelled Sauce Pans, Basting Spoons, Brass Candlesticks, Braes Cocks, Brass Stair Rods, Braces and Bits, Measuring Tapes, Superior Waiters, Curry Combs, Tesces, Coil, Birth, Tongues, Stretch and Breast Chains, with a variety of other' goods, all of which will be mt.0..1 at mod erato terms. . aplB SKIRTS 1 SKIRTS! 1 Bishop's Skirts; Quilted Hooped Skirts; Holmes' Hooped Skirts; Misses' C irdid Skirts; Ladles' Corked and Q u ilt e d skirts, white and colorel ; new atipply just opened, at JOS. HORNE'S, deb 77 Market street. INTER GLOVES.—A full supply of v Cloth, Silk and Merino, of various slam at low prii HOIINVB, TT Martel itreet. ORPEDOES.-100,000 No. 1, just receiv ed and for gale by aliltidEli 6 ANDIREON, ifick Se Ward Mu* C1C00..". Tyr.. rev