I have thought it proper to refer to those iacts, not only to explain the couses \ of the delay in filling the commission, bsit to call your attention to the propriety of increasing the compensation of the com misfcionirs. The office is one of great labor and responsibility, and the compen sation should be such as 10 command men of a higl) order of talents and the most unquestionable integrity. The proper disposal < f the mineral lands of California is a subject surrounded by great difficulties. In my last annual message 1 recommended tire survey and 6aleofthem in small parcels, under such restrictions as would cfl'cc ually guard a gainst monopoly and. spocu a ion. But * , upon further information, and in deference to the opinions of persons familiar with the subject, 1 am inclined to change that recommendation, and to advise that they be permitted to remain, as at present, a common field, open to the enterprise and indnsii'y of all our citizens, un'il further experience shall have developed the best policy to be ultimately adopted in regard 10 them, his saftfr to sutler the incon veniences that now exist, for a short per iod, than, by premature legislation, to las ten on the country a system founded in trrui, which may place the whole subject boyondlhe future control of Congress. The agricultural lands should, however be surveyed and brought into market witli as little delay as possible, that the titles may become settled, and inhabitants stimu lated to make permanent improvements, and enter on the ordinary pursuits of life. To effect those objects it is desirable that the necessary provision be made by law for the establishment of land offices in Cal ifornia and Oregon, and for efficient pros ecution of the surveys at an early day. Some difficulties have occurred iu organ izing the Territoiial governments of New Mexico and Utah ; and, when more ac curate informatian shall be obtained of the causes, a further communication will be made on that subject. In my last aunnal communication to Congress 1 recommended tiic establish ment of an Agricultural Bureau, and 1 lake this occasion again to invoke your favorable consideration of the subject. Agriculture may justly be regarded as •the great interest of our people, Foor diftliß of our active population are employ ed in the cultivation of the soil, and the rapid expansion of our settlements over new territory is daily adding to the number of those engaged in that vocation. Justieo and sound policy, therefore, alike require that ,l.l)e Government should use all the m, aus au thorized by the Constitution to promote the interests and welfare ufihat important class of Obr fellow citizens. And yet it is a singular fact that, whilst the manufacturing and com mercial interests have engaged the altention of Cougress during a largo portion of every session, atidour statutes abound in provisions for their protection and encouragement, little •has yet been done directly for the advance ment of agriculture. It is time that this re proach to our legislation should be removed ; and 1 siueerely hope that the present Congress will not close their labors without adopting ef ficient means to supply the omissions of those who have preceded them. An Agricultural Bereau, charged with the duiy of collecting and dissemiuating correct information as to the best modes ot cultiva tion, and of the most eflectual means of pre serving and restoring the fertility of the soil, and of procuring and distributing seeds and plants and other vegetable productions, with •instructions in regard to the soil, climate and treatment best adapted to their growth, could •not fail to be, in the language of Washington, in his last annual message to Congress, a "ve ry cheap instrument of immense national ben efit." Regaling the act of Congress approved 28th September, 1850, granting bounty lands to persons who iiad been engaged in the mili tary service of the country, as a great meas mof national justice and munificence , an ious desire has been felt, by the officers .entrusted with its immediate execution, to give prompt efTeet to its provisions. All the meatis within their control were, therefore, brought in'.ci requisition to expedite the adju dication of claims, and 1 am gratified to be able to state that near one hundred thousand applications have been considered, and about seventy thousand warrants issued within the short space or nine months. If adequate pro vision is made by law to carry into effect the recommendations of the department, it is con fidently expected that, before the close ol the next fiscal year, all who are entitled to the benefits of the act will have teceived their warrants. The Secretary of the Intßrior lias suggested in his report various amendments of the laws relating to pensions and bounty lands, for the purpose of more effectually guarding against übuses and frauds on the Government, to all of which L invite your particular attention. The large accessions to our Indian popula lion consequent upon tho acquisition of New Mexico and California, and the extension of our settlements into Utah and Oregon, have given increased interest and importance to our relations with the aboriginal race. No marerial change has taken place, within the last year in the condition and prospects ol the Indian tribes who reside in the North western Territory and west of tiie Mississippi liver. We are at peace with all of them; and it will be a source of pleasure to you to learn that they are gradually advancing iu civ ilization and the pursuits of social lite. Among the Mexican frontier, and in Cali fornia and Oregon, there have been occasion al manifestations of unfriendly feeliug, and some depredations committed. I am satisfied, however, that they resulted more from the destitute and starving condition of the Indians than from any hostility towards the whiles.— As the settlements ot our citizens progress .towards them, tho game upon which they mainly rely tor tubsistance is driven off or destroyed, and the only allerm five left to them is starvation or plunder. It becomes us to consider, iu view of this condition of things, whether justice and humanity, as well as un •enlightened economy, do not require that, in stead of seeking to punish them lor offences which are the resultof our own policy towards them, we thould not ptovide for their imme diate wants and encourage them to engage in agriculture, and to rely on their labor, ytslead of the chase, for the means of support. Various important treaties have been nego tiated with different tribes during the year, by which their title to large and valuable tracts of country has been extinguised, all of which will, at the proper time, he submitted to the Senate for ratification. The joint commission under the treaty ot Guadalupe Hidalgo has been actively engaged in running and marking the boundary line be tween the United States and Mexico. It was stated, in the last annual report of tho Secre tary of tbe Interior, that the initial point on The Pacific and the point of junction ol the Gila with the Colorado river had been deter mined, and the intervening line, about one hundred and fifty miles in length, run and marked by temporary monuments. Since that time a monument of marble has been erected at tbe initial point, und permanent landmarks of iron have been placed at suita tle distances along the line. ( Continued on second Page.) FSRE PROOF CHESTS, FOR BOOKS, PAPERS, JEWELRY, &c. EVANS & WATSON, !MANDERS. Fire'and thief 1 roof IRON CHESTS, warranted to stand more heat than any other chests in the country. Also, Potent Air Cham be IRON CHE 'l'S, 1700 now iu use. They alsocontinne to make tho ordinary Firo Proofs at very low prices. We, tho undcraigred 'were present on the 11 day of September, when Messrs, Evans 4- Wat son tested ono of their Salamauder File Proof Cliest3, at which time they consumed five cords cf wood over it, commencing at 9 A. M. and continuing until 2 o'clock, P. M., making vr hours intense heat, amounting to a white neat. The Chesta remained in the fire until the next morning, when it was opene in our presence, and all the books and papers taken out, having been preserved entire. 'J'he above named Chest, together with tho books and papers, may he examined by catling at the Store ot Evans & Watson, 83 Dock street. THUS. HANSELL, 13th St., above Arch. SAMUEL L. DAVIB, lll.N. Third ot. WILLIAM HARPER, Jr, Messrs. Evans & Watson: Gentlemen -llavirg been present when the contents of the Chest alluded to in the above ceitifioatc wcro exposed to view, I take pleasure in adding iny testimony to tho perfect security of the papars. No mark of fire was apparent on any of tbcnr. Respectfully. 8. V. MERRICK. Philadelphia, Sept 16. BALTIMORE, June 18. Messrs. Evans do 'Vatson, Philadelphia; Goiitlcmen—We have much pleasure in re commending your Firo Proof Chests to the no tice of tho public—the ono we purchased from you having saved our books and contents efloc tually, after undergoing a very severe boat during the fire, which destroyed the entire block of buil dinga on Aich street wharf, on tho Schuylkill, on the 6th of June, 1849. Yours, very res ully, RUBBEL & GILI-INB. Seal and Letter Copying Presses, Fire proof Doors for Banks and Stores; Patent Slate Lined Refrigerators, warranted superior to all others, Water Filters, Truck Wogon6 for Stoics, Sho.v cr Baths of tho best quality, June sth, 1851—ly ESSENCE OF COFFEE. ABOUT two years ago a new discovery was made in Europe, consisting of a substitute for the ordinary store coffee, called Essence of Coflee, which has gone into gen eral use with astonishing rapidity, not only among the poorer classes, who at once dis pensed with the use of,the celebrated Chick ory Coffee, but is now in general use in the wealthiest families and the first hotels, and I is highly recommended by the medical fac ulty. | it is extracted from pure, wholesome veg etables. and excels all similar preparations that have ever been offered to the public, either in this country or iu Europe. Its su perior quality has already been attested to in the cities by some of the most eminent phys icians, and a number of the most distinguish ed of the clergy and other highly respectable citizens. Coffee made from this essence ac- I cording to the prescription obtains a more | delicious and pleasant favor than the com- I moo store coffee, and is certainly more ' wholesome, especially for persons in deli cate health, which will be admitted by eve ry physician who will take the pains to test the uatute and properties of this essence. One paper costing only 12 J ms., is equal to four pounds of store coflee, will be bright and clear without the application of any other ingredieut to clarify or settle it. The public are therefore invited to "ive this es sence at least a trial before they condemn it. A respectable merchant of Luzerne coun ty in writing of it saj s: "My customers have been using of the above Essence for some months past with general satisfaction ; and Ido not hesitate to recommend it to the public. HENDERSON GAYLORD." Manufactered by G. Hummel, Bohler & Co., 718 Callowhill street Philadelphia. For sale by GEORGE WEAVER, Blooms burg, by whom merchants can be supplid a! manufacturers prices—freight added. Bloomsburg, July 31st, 1851.—3 m. OL OCXS toaCSe classed with the vast amount of " Remedies of the day it claims for itself a greater healing power, in all diseases, than any other preparation now before the world; and has sustained itself for eight years by its sui>erioi medical virtues, nnd, until this reduction, commanded double the price of any other article in this line. TFETICE PARTICULARLY, this article acts with greet heaj ing power and oertaiuty, upon the Blood, Liver, Kidneys, Lunge and all other organs, upon the proper action of which life and health depend. This meilisba has a justly high repute as a remedy for Dropsy and Gravel, and all diseases of that nature. It may be relied upon when tlie intelligent phyeioian has abandoned his patient, —and for these distressing diseases, more especially DROPSY, the propri etor would earnestly and honaaliy recommend it. At its present price H is easily obtained JJ all, and the trial will prove the article to be the Cheapest Medicine in the World! ty Please ask for pamphlets the agents give them away they contain over sixteen pages of receipts, (in addition to fu) medical matter) valuable for household purposes, and whict will save many dollars per year to practical housekeepers. These receipts are introduced to make the book of great value, aside from its character as an advertising medium fos the medicine, the testimony in favor of which, in the form of letters from all porta of the country, may be relied upon. ty* '• Vaughn's Vegetable Lithontriptic Mixture" —lite Great American Remedy, now for sale in quart bottles at |1 each, small bottles at 50 cts each. No small bottles will be issued after the present stock is disposed of. Principal Office, Buffalo, N. Y., £O7 Main Street, G. C. VAUGHN. Sold Wholesale and Retail by OLCOTT McKESSON & CO., 127 Maiden Lane, New York City. N. B.—All letters (excepting from agents and dealers witn whom he transacts business) must be post paid, or no attention will be given to them. AGENTS.—E. P. LDTZ, Bloomsburg; O. F Moore, Danville; Jno. W. Friling, Sun bury, M A M'Cay, Northumberland; John Sharpless, Cattawissa ; J K Millard, Espy town ; A. Miller Berwick ; Charles Seybert- Beach Haven.Oct. 31, 1850.-ly Philadelphia & Reading Rail Road. REDUCTION of frieght on Merchandize, to commence March 1, 1851. PATES OF FREIGHT PER 100 LBS. Between Pottsville and Philadelphia. ARTICLES TRANSPORTED. —Is* Class.—Bi tuminous Coal, Bricks, Ice, Iron Ore, Lime stone, Pig Iron, Plaster, Slate, Tiles, 9 cts. 2d Class. —Blooms, Burr Blockt, Cement. Grindstones, Guano, Laths, Pilch, Railroad Iron, heavy, Rosin, Salt, Sills. Shingles, Tar, Turpentine, Timber and Lumber, 10 cts. 3rd Class. —Ale, Beer, and Porter, Ashes, Pot & Pearl, Bark, Barley, Bones & Horns, Coffee, Cotton, Whiskey, & Domestic Li quors, Grain, Iron Castings, rough; Rolled, Bar or Hammeted Iron, Boiler Plates, Flat Bar Rail Road Iron, Lead and Shot, Mo lasses, Potatoes, Nails & Spikes, Salt Provi sions, Sugar, Saltpetre, and Tobacco, un-. manufactured, 12$ cts. Flour per barrel, 25 cts. 4 th Class. —Apples, Bran, Butler, Cheese Cordage, Earthen Ware, Eggs, Groceries (except those stated) Hemp, Hardware, and Cutlery, Hollow ware , Lard, Leather, Live Stock, Manufactures of Iron, as Machinery; Oil, Oysters, Paints, Raw Hides, Rags, Rus sia Sheet Iron, Seeds, Steel, Sweet Potatoes, Tallow, Vinegar and Wire, 17 els. sth Class. —Books and Stationary, Boots & Shoes, Camphine, and Spirit Oil, China, Glass and Queensware, Cigars, Confectionery, Dry Goods, Drugs, Fresh Fish, Meat & Fruit, Fo reign liquors, Hops, Spirits of Turpentine Teas, Wines and Wool 22 ots. March 13, 1851. HOVER'S INK MANUFACTORY, REMOVED TO No, 144 Race Street, (Between 4th & sth, opposite Crown St.) PHILADELPHIA, WHERE the Proprietor is enabled, by increased facilities, to supply the growing demand for HOVER'S INK, which its wide spread reputation has created. This Ink is now so well established in the good opinion and confidence of the A merican Public, that it is scarcely necessary to say anything in its favor, and the manu facturer takes this opportunity to say that the confidence thus secured shall not be abused. In addition to the various kinds of Wri ting Ink, he also manufactures Adaman'ine Cement for mending Glass and China, as wel l as a superior Hair Dye; a trial only is ne cessary to insure its future use, and' a Seal ing Wax, well adapted for Druggists and Bottlers, at a very low price, in large or small quantities. Orders addressed to JOSEPH E. HOVER, Manufacturer, No. 144 Race Street, Between 4th & sth, opposite Crown St., Philadelphia. Sept. 18, 1851.-3 m. WINDSOR AND COMMON CHAIR made lo order of any desirable style at th chair manufactory of B. HAGENBUCH Bloomsburg, May 16th 1850. CHERRY PECTORAL: For ihetCure of COUGHS, COLDS, HOARSENESS, BRON CHITIS, CROUP, ASTH MA, WHOOPING-COUGH AND CONSUMPTION. In offering to tho community this judly ccl ebrstcil remedy for diseases of the threat and lungs, it is not our wish to trifle with the live? oi health of the atllicted, but f-arkly to lay be fore them tho opinions of distinguished men .Sr some of the evidence- of its succors, from which tliev car udgc foe thin.Ftlvre. Wire ct-re.y pteOge ourtoiWb lo inakc no wild nee tions or false statements of its efficacy, nor will we hold out any hope to suffering humanity which fao's will not warrant. Many proofs arc here given, and we solicit an inquiry from the public into ult we publish, for lingussorcd they will find them pertcclly ri lia ble, and the medicine worlhy tbcji best ccufi douce and patronage. PROF. CLEVELAND, of Bcwduin sol lege, Maine, Writes—"l hove witnessed tha effects of your 'CHERRY PEGTORAL'in my own fondly and that of my fiiends. and it gives ine satis faction to state in its favor that no medicine I hive ever known has proved so emiuently suc cessful in cuiing diseases of the throat and lungs." REV. DR,OSGOOD Writes "That ho considers 'Cherry Pectoral' the best medicine for Pulmonory Affections ev cr given to tho public,' snd stales that "bis daughter ofler boing obliged to keep the room four months with a severe settled cough accom panied by raising of blood, night sweats, and the attendant symptoms of Consumption, com menced Ihe use ef the 'Cherry Pectoral,' and had completely recovered," EX—CHANCELLOR KING, fNcw ork soys. "I have been u greut suffer er with llronchclis, and but for the use of tho •CULIIRT PSCTOBAL' might have continued to be so for many years to conic, but that bus cured mo and 1 am happy to bear testimony to its tfi cacy," From such testimony we ask tho public to judge for then-srives, HEAR THE PATIENT, Dr, Ayer—Dear Sir; For two years I was ffliclcd with a very sevcie cough, accompanied y spitting of blood and profuse night sweats, ly tho advice of my attending pbysiciaa 1 was nduced to use your Cherry l'cctsral, and con tinue - to do so till I consideied myst If cured, and ascribe the effect to your prcparnti.m, JAMEs RANDALL, Hamdcn ss. Springfield, Nov. 27, 1848, This duy appeared the above named James Randall, and pronounced flic above statement true in every respect. LORENZO NORTON, Justice. THE REMEDY THAT CURES. POHTLAN n, Mc , Jan. 10,1847. Dr. Ayer; I have been long afflicted with Asthma which grew yearly worse until last au tumn, it brought on a cough which confined me in my chamber; and began to assume the alarm ing symptoms of consumption. 1 had tried the best advice and the I -est medic'no to no purpose, until I used your Cherry Pectoral, which has cutcd me, and you may well believe me. Gra'e ullv yours, J.D.PHELPS, If there is any value in ihe judgment of the wise, who speak from experience, here is a med icine worthy of the public confidence, Prepared by J. C. -Iyer, Lowell. Mass., Sold by E P.I.UTZ, B.oomsbnrg A B WILSON, Berwick Jan, 16,1851.-4 m. AN ADVERTISEMENT THAT APPEALS TO THE SOUNU SENSE OF THE COMMUNITY. Standard Medicines, The following unequalled series of Family Medicines may be depended npon with the u most confidence, They have the approbation of the best physicians in the country, and arc recommended by -ill who have used them as superior to any family medicines known. They have been been before the Public FOR FIVE YEARS, during which time more than 6,000 certificates have been received from emi nent public men and others, and are now un file in the Company's Office. TLIEY ARE COMPOUNDED with the ut most care and skill, and the Ingredients are thor oughly tested by scientific chemists, so that medicines of a uniform and reliable quality are guaianteed in all cases. The Gricfonberg VEGETABLE PILLS, Are par ticularly valuable for Ihe prevention and euro of Fevers in general, all Billious anc I.ivci Com plaints, Jaudice, Goneial Debility, Common and Hick Headache, Dyspepsia, Heart Bum, Cos tiveness, Giiping, Urinary Diseases, Obstruc tions of the Menses. Influenza, Asthma, and for a variety of other Chronic Diseases; in Ulin for all ordinary family uses. Full directions for the various Disea ses accompany each box, Price 25 els. a box. THE DRNCRCNBERG DYSCN T E R Y SYRUP. A speedy and infallible remedy in Diarrhoea, Dysentery, Bloody Flux, Cholera Morbus, Cholera Infantum, and the Asiatic Cholera, if taken with the first symptoms, viz . vomiting and diarrhoea. It Dever fulls to cure the worst possible cases of bowel complaints, generally in a few hours, seldom beyond a day. It is Purely Vegetable, at d taken in ulniOßt any quantity is perfectly harmless. Tho Gtaefcnberg GREEN MOUNTAIN OINTMENT. Invaluable for Burns, Wounds, Sprains, Cbillblains, Corns, Soies, Swellings of all kinds, Rheumatism, Erysipelas, Bronchitis, Scrofula, ' leers. Pains in the Side and Hack immediatey relieved, inflammation of the Bow els, and for all cases where there is inflammation. THE GIIAEFENBERG MANUAL (IF HEALTH. A Complete hand-book of medicine for fami lies. Price 60 cents. Office 214 Broadway, N. Y. CA UTIO N. The public is requested to bear in mind that everything prepared by (he Graefenbcig Com pany has their seal upon it. Spurious articles have been issued closely re sembling the genuine in every particular except the seal, and the utmost care should he observed befoie purchasing. AGENTS,— Thomas Ellis, and E. P. Lutz, Bloomsburg; Benjamin Bei ber, Caltawissa, Peter Ent, Light Street. Bloomsburg, Jan. 23, 1851-6 m, TAILORING IN LIGHT STREET JAMES SMITH Invites'tbe attention oi the fashionable in Light Street to his slsie of cutting garments He makes them in the best and most tasty maimer, and can can ensure satisfaction in his warkmatiihip. He receives the latest fashions, and when cutting onlp is desired, the work is marked carefully for the maker. ET'All kinds of country produce taken exchage for work. Light Street, Feb. 14, 1850. ANOTHER SCIENTIFIC WONDER I? 12 3> £3 E Stf 8 THE JEUE DIGESTIVE FLUID, on A Gieat Ihvpepsia curer, Prepared from IIEMIET, or the fourth Stomnch of Iho Ox, after directions of Baron Liebig, tiro great Physiological Chemist, by J. S. Houghton, M. D., No. 11, North Eighth Street, Phila delphia. Pa. This is a truly wonderful remedy fo r 'Tnd gostiqn, Dyspepsia, Jaudire, Liver Com plaint, Constipation, and Dobilily, Curing alter Nature's own method, by Nature's own agent, the Castric Juice. Ce*" Half a spoonlul of litis Fluid, infused in water, will digest or dissolve, Five Poundt of Boast Beef in about two hours, out of the ; stomach. DIGESTION. Digestion is Chiefly performed in the stomach by the aid of a fluid which freeljr exudes ftom the inner coat of that organ, when in a state ot health, eullcd the Gastric Juice. This fluid is the Great solvent of the Food, the Purifying, Preserving, and Stimula ting Agent of the stomach anJ intensliues. Without it there will be no digestion,—no conversion of food into blood, and no nu trition of the body; but rather a foal, torpid 1 , painful, and destructive condition of the whole digestive apparatn*. A weak, half dead, or injured stomach produces no good Gastric Juice, and honce the -'i*®*** dir ressand debility which en.rg.3. Persia ANU RENNET. — Pepsin is tn chirr element, or great Digesting Principle of (hoc Gastric Juice. It is found in great abun dance HI the solid parts of the human stom ach afterle ith, anil sometimes causes tha stomach to digest itself, or eat i'sclf up. It is ulso found in the stomach of animals, as. the ox, calf, &o. Jt is the material used by farmers in makirg cheese, called Rennet, the effert of which has long been the spe cial wonder of the dairy. The curdling of milk is the first process of digestion, lien net possesses astoiiishi' g power. The stom ach of a calf will curdle nearly one thou sand times its own weight of milk. Baro Liebig states that, 'One part of Pepsin dm solved in sixty thousand parts of water, wil digest incat and other food." Diseased stomachs produce no good Gastric Juice Rennet or Pepsin. To sltow that this want may be perlectly supplied, we quota tha following SCIENTIFIC EVIDENCE! BARON LIKBIU, in Lis celebrated work on nimal Chemistry, says : "An Artificial Di estive Fluid analago us to the Gastric Jtiico, may he readily prepared from the nucoua gniembrane of the stomach of the Call, which various articles of food, as meat and eggsj will be softcneu, changed, and diges ted, just in the same manner as they would be in the human stomach." Dr. l'creira, in his famous treatise on "Food and Diet," published by Fowlers Si Wells, New York, page 35. states the same great fact, and describes the method of prep aration. There are few higher authorities than Dr. Poreira. Dr Combe, in his valuable writings on the "Physiology of Digestion," observe that "a diminution of tho due quantity of the Gastric Juice is a prominent and all-pre vailing cause of Dyspepsia;" and he state, that "a distinguished professor of medicine in London, who was severely afflicted win this complaint, finding every thing else to fail, had recourse to the Gastric Juice, ob tained from the stomach of living animals which proved completely successful." Dr. Graham, author of the famous work on "Vegetable Diet," says: "it is a remar kable fuel in physiology, that llio stomachs of animals, macerated in water, impart to the fluid the properly of dissolving various articles of food, and of effecting a kind of artificial digestion of them in no wise dif ferent from the natural digestive process." Dr. Simon's great work, the "Chemistry of Man," (Lea & Blam-hard, Phi la.. 1846, pp. 3212): "The discovery of PEPSIN fo IDS a hew era in the chemical history of Di geslion. From recent experiments we know that food is dissolved as rapidly in an artificial digestive fluid, prepared from IVp sin, as it is in the natural Gastric Juice it self." Professor Dunglison of the Jefferson Col lege, Philadelphia, in his great work on Hu man Physiology, devotes more than fifty pages to an examination of this subject. His experiments with Dr Beaumont, on the Gastric Juice, obtained from the living hu man stomach and from animals art) well known. "In oil cases," he "digestion occurred as perfectly in the artificial as the natural digestions." As a DYSPEPSIA CURER, Dr Houghton'* preparation of Pepsin has produced the most marvellous eflects, curing cases of De bility, Emaciation, Nervous Decline, and dispeptic Consumption, supposed to be on the very verge of the grave, h is imposs ble to give the details of cases in the limit of this advertisement—but authenticate certificates have been of more than two hun dred Item-likable Cures, in Philadelphia, New York, and Boston alone. These worn nearly all desperate cases, and the cure* were not only rapid and wonderful, but per manent. It is a great Nervous Antidote, and par ticularly useful for tendency to billious dis order, Liver Complaint, Fevor and Ague, or badly treated Fever and Ague, and the ev il eflects of Quinine, Mercury, and other drug upon llio D.gestive organs, after a long sick ness. Also, for excess in eating, and the too free use of ardent spirits. It almost rec onciles Health with intemperance. OLD STOMACH COMPLAINTS. —There is no form nf Old Siouu>J CompWnts which it does not seem to reach and remove at once. No matter how bad tWy may be, it gives Instant Belief! A single dose removes all the unpleasant symptoms, and it only needs to bo repeated, for a short time, to make these good effects permanent. Purity of Blood and Vigor of Body, follow at once. It is particularly excellent in cases of Nausea Vomting, Cramps, Soreness of the pit of tho Stomach, distress after eating, low, cohf stato of the Blood, Heavir.oss, Lowi ess of Spirits, Despondency, Emaneiation, Weak ess, tendency to Insanity, Suicide, &c. Price, ONE DOLLAR per bottle. One bottle will often eflect a lasting curq. PEPSIN IN POWDERS, l is* Sent by Mail Free of Postage. For convenience of sending to all parts of the country, the I igestiveMal'erof the Pep sin is put up in the form of Powders, witfi directidus to bo dissolved in water or syrup, by the patient. These powders contain just the same matter as the bottles, but twice the quantity for the same price, and will be sen by mail, F'ree of Postage, forOno Dollar sent (post-paid) to Dr J S Houghton, No 11 North Eighth street Philadelphia, Pa. Six packages for five dollars. Every package and bottle bears the written signa ture of J S HOUGHTON, M D., Sole Propria tor. Sold by agents in fevery town in the ITni ted Slules, and by respectable dealers in Medicines generally. Ageuts for Bloomsburg, JOHN R. MOV ER, E. P. LUTZ. Books! Books! Joseph Swartz has just received a new lot of Literary, Historical, Religious, Poetical Miscellaneous and School books, to which he invites tho attention of the reading pubflo of Bloomsbqrg.