New Vaccine To Fight Salmonella In Eggs
ATHENS, Ga. Developing
an oil emulsion vaccine to
reduce the possibility of Sal
monella enteritidis entering
chicken eggs is the aim of scien
tists at the Agricultural Re
search Service’s Southeast
Poultry Research Laboratory in
Athens, Ga.
i Immunologist Peter Holt, re
tired veterinarian Henry Stone
and immunochemist Cam
'Greene have developed an oil
emulsion vaccine of inactivated
,S. enteritidis that protected hens
exposed to the organism.
< Hens infected with Sal
monella can transmit the organ
ism into their eggs. People who
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eat infected eggs can gei sal
monellosis, a disease character
ized by nausea, vomiting and
severe diarrhea.
In studies at Athens, birds
were vaccinated twice and then
exposed to S. enteritidis. The
new vaccine reduced S. enteri
tidis shedding in the birds’ feces
by 10 to 40 percent. A patent for
the vaccine has been filed and is
available for licensing.
The experimental oil emul
sion vaccine is more effective
than commercial vaccines be
cause it boosts levels of antibo
dies that the hens produce to
fight the infection, reducing S.
enteritidis inside their intestines.
UY
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This, in turn, decreases the
chance that the bacterium will
spread further through the
birds’ bodies, or that it will be
shed in their feces.
An improved vaccine that re
duces Salmonella shedding
would be helpful to the poultry
industry, since this is the pri
mary method by which Sal
monella infection spreads
through a flock. Vaccinating
poultry flocks against Sal
monella is an important practice
within the industry today.
Approximately 25 million
doses of S. enteritidis vaccine
are used annually in U.S. poul
try, while 50 to 75 million doses
are used worldwide.
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