A2O- Lancaster Farming, Saturday, May 14, 1994 Efforts Under (Continued from Pago Al) practicing dairy veterinarian, many hopes of an aggressive, pre ventative animal health program depend on how well cooperation and funding continue to support the young program. The benefits of such an under taking are many and the implica tions for human health are great. The reason for the need of such a program are evident. Background During the mid-80s, there were several disease problems that were identified in the state. The one that had the niost impact was avian influenza, according to Card. “And then it became apparent that there was a fairly high inci dence of Johne’s disease in cattle,” he said. “Prior to that, we had a problem with tuberculosis, actual ly it was avian T.B. but it was affecting swine. Then psuedora bies in swine. All of these diseases are relatively difficult to control, without good laboratory diagnosis and continued testing and surveillance. “At the time, I was at Penn State, department head of veterinary sci ence, and several of us had made the suggestion at that time inlcuding the faculty, the dean of the vet school at the University of Pennsylvania and said we should really pull together these resources we have, because we had people up there at Penn State who were good at various types of diag nostic activities. “(University of Pennsylvania) had people who were good at vari ous types of diagnostics, and of course Summerdale has a some what different approach, because they do a lot of import and export testing and a lot of regulatory test ing, so they do a lot of high volume tests that are done rapidly,” Card said. “So each lab had a different emphasis “Suggestions were made and I think a white paper was written at New Bolton that suggested that was a way that we might go to make more effective the resources present m the state. “And that’s what happened. So the act was written, passed in 1988, as legislation, and was enacted in 1989, signed into law “At that time, they appointed commissioners six farmers, three vets, tour legislators (the political minority and majority chairmen of the Senate and House Agricultural and Rural Affairs committees), and the secretary of agriculture as the designated chair of the Animal Health Commission. “The verbiage in the enactment was that they wanted to develop a tripartite lab system, pulling together or integrating the resour ces of the Penn State Univesrtiy, University of Pennyslvania and Summcrdale (the PDA diagnostic lab). That was the main objective when I came here almost two years ago,” Card said. “Secondly, they wanted to deve lop a stronger research focus on animal disease by trying to attract external funding, from other than the state line funding that comes from PDA, they wanted an integra tion of research activities, evalua tion of results and dissemination of information. “So, what they wanted really was a system that would look at research in animal health in the state and make it more available to people who could use it, and thus provide more knowledge for farmers. ay To Build Animal Disease Fighting Ability field investigations and disease surviellance,” Card said. According to the director, the law also called for the develop ment of a “cadre” of scientists from Penn State, University of PDA Publishes Johne’s Disease Pamphlet VERNON ACHENBACH JR. Lancaster Fanning Staff HARRISBURG (Dauphin Co.) While the Animal Health and Diagnostic Com mission of- the state Depart ment of Agriculture is attempting to bring the animal diagnostic laboratory system up to a modem level, it is also actively working to combat animal disease now. This week a pamphlet was printed by the PDA that com bines information about one of the most worrisome diseases to the dairy industry, Johne’s Disease. The text of the pamphlet, distributed by the PDA, was prepared by R.H. Whitlock, L.J. Hutchinson, and R.W. Sweeney, of the Pennsylvania Johne’s Research Team, and C. Rossitcr, of Cornell Uni versity in November last year. According to the text, the disease is caused by Mycobac terium paratuberculosis, and it was first identified by Dr. Heinrich Albert Johne. It is slow-growing, requiring 14 weeks to grow under ideal conditions and it affects cattle, sheep, goats, deer, llamas, buffalo and other ruminants, such as whitetail deer. It can be carried without symptoms for two to several years after infection. Infection can come from birth or an infected environment. Calves can get it from dams while in the uterus, from ingesting pieces of manure, or from the teat or udder of a cow. If one shows signs of it normal appetite, but weight loss and diarrhea the authors of the pamphlet state that, “15-20 other animals arc likely mlcclcd The clinicl case represents only the ‘tip of the iceberg’ ol Johnc’s infec tion However, only 40-50 percent ol all mlcctcd cattle can be detected with even our most sensitive (lest). According to the experts, if 25 to 30 animals arc lest posi tive on a single herd lest of 100 adults, it suggests that probab ly 50 percent or more arc infected. Estimates arc that it may cause a loss of about $5.8 mil lion per year to the Pennsylva nia dairy industry, and it is also prcvclant in other large dairy slates, according to researchers. And while calves bom with it would only show the disease after they are at least two years old, and can represent a signif icant economic loss to dairy farmers, the researchers state that having it discovered on a farm doesn’t necessarily mean the end of business. The following is that por tion of the pamphlet that tells about managing a herd for Johne’s control. The full pam phlets should be available through the state Department of Agriculture, and also Penn, or Summerdale to “intervene on a more scheduled basis in disease crisis.” “They wanted us to become awarp of disease processes that were going on in domestic animals through the local extension office soon. Managing Johne’s How is Johne’s disease con trolled on the farm? The general strategy: There is no treatment for Johne’s disease. The key to preventing, con trolling and eliminating Johne’s in a herd is MANAGEMENT. Testing is a valuable tool to evaluate the extent of the infection, to identify infected animals, determine the inten sity of a control program, and to monitor progress of control efforts. The general strategy for controlling infection is to identify and adopt appropriate management and sanitation procedures for the farm that will best accomplish three main goals: 1. Prevent highly suscepti ble newborn calves and young animals from ingesting man ure from infected adults, be it from the dam, the environ ment, or the feed (or water). 2. Prevent all other suscep tible animals from the gesting low levels of infected manure, especially by contamination of feed and water. 3. Reduce the total farm exposure level to Microbac terium paratuberculosis by removing the bacteria from the environment and reducing the number of infected ani mals that are shedding the bacteria. Goals one and two are achieved by sanitation and accepted good management practices, which benefit the farm as a whole. Goal three is accomplished by more rigorous sanitation and testing and culling specifi cally lor Johnc’s disease. For a given level of infec tion, detecting and culling infected animals early in die disease will speed the rale at which Johnc’s is reduced or eliminated from a herd. Specific recommendations: The specifics and intensity of a Johnc’s disease control strategy in cattle will vary with the individual farm situa tion. To be relevant and effec tive it must be designed to fit the immediate and future goals of the farm, and avail able resources. Many specific methods can be used to accomplish the three main goals, but the most effective and practical mea sures to break the cycle are outlined. • Management of new born calves and young ani mals is critical and is the most effective place to put the effort: Calves should be bom in an area that is dry, clean of man ure, and well bedded. Areas used only by one or a few ani mals at a time and for materni ty ONLY should be the goal. Clean tests and udders are a must. in the state, and then to intervene on a planned basis rather than reactionary.” There were three major respon sibilities, according to Card. He said the goals were to first The most effective control measure is to remove newborn calves from the dam and maternity area immediately, thus ELIMINATING the chance to ingest manure in attempts to find the udder and nurse. Feed newborns colostrum, ideally within one to two hours, from only healthy appearing dams, who are less likely to pass M. paratubercu losis into the udder and milk. Milk replacer eliminates the nsk of possible infection from feeding whole or pooled milk to calves. Replacer should be seriously considered especial ly in herds with significant infection. Young calves and heifers should be housed separate from adults and should have no direct contact with manure from adult cattle. Separate facilities are ideal but sections protected by partitions, dry alley-ways or buffer zones, or low traffic zones are effective. Do NOT contaminate feed or feed mangers with manure from feet or equipment. • Management to prevent low levels of exposure in all older animals is important: Prevent manure contamina tion of feed and waterers. IX) NOT use the same loader or equipment to clean manure and to load feed. DO NOT walk in the feed bunks. Eliminate or fence ani mals out of natural water sour ces that they drink, that also are slow moving or stagnant, and collect run-off containing manure that animals stand in. • Identifying and remov ing infected animals and their manure is necessary to reduce the risk of continued exposure for ALL animals: Test the herd to identify infected animals that arc, or probably will be shedding the bacteria. Based on evaluation of results, infected animals, should be culled as heavily as economics permit. The most severe should be culled first. An initial lest of the whole herd followed by aggressive culling is very effective in ini tially reducing the prevalence in the herd. Appropriate man agement should be started at the same time. Testing and culling, com bined with management, will control Johne’s disease more effectively and in less time than partial culling and man agement or either alone. Frequency of testing and culling will depend on what is practical for the farm. The simplest and most effective approach to take in any infected herd is to man age all animals as if they are infected and as if all manure is guilty. This management attitude works all the lime, and is espe cially important if testing and early culling is not practical. Attempt to recognize and strengthen the system, build the diagnostics program, which had received little attention since it was constructed during the 19505, and getting more people out in the field (Turn to Pag* A2l) cull animals suspicious with clinical signs, earlier, before they further contaminate facil ities and lose salvage value. These animals are shedding billions of organisms each day. If uncertain, ISOLATE or cull anyway, and test to con firm for your knowledge. Sanitation has no substitute. Remove manure as thorough ly and as often as possible. Always strive for more often. Spread manure on cropland, not on pasture to be harvested or grazed the same season. • Reduce the risk of intro ducing infected animals into the herd, especially when eli mination of the infection is the goal: Be cautious and investigate animals to be purchased. Purchase animals from test negative herds, herds with no history of Johne’s and/or farms that look clean. Reduce risk by prior testing with serology or by fecal cul ture immediately when ani mals arrive. The goals of a Johne’s Dis ease control program are several. In herds with low to mod erate infection (1 percent or fewer clinical cases per year), wise use of a combination of testing, culling and manage ment can be expected to reduce the clinical disease to zero within 1 to 3 years and most infection in 5 to 7 years. Thus, as the herd turns over, each succeeding generation will have fewer infected ani mals, eventually all of which will be non-shedders. Finally, the infection will be eliminated. Complete elimination of infected cattle is likely to take many years alter Johne’s dis ease becomes invisible in the herd. Preventive management should remain in place other wise Johne’s disease is likely to recur. With repeated negative herd tests, herds can qualify for paraluberculosis test nega tive certification status in PA and NY. These stale programs are consistent with the Nation al Paraluberculosis Certifica tion Program Guidelines adopted by the USAHA, November 1993. Herds with more severe widespread infection will require aggressive control programs and many years to eliminate Johne’s disease. However, a practical control program and sound herd man agement can be expected to eliminate clinical disease in these herds and reduce the economic impact of Johne’s in the herd to a minimum. For more information on control programs, contact in New York-NYS Diagnostic Laboratory, ITHACA 14852 607-253-3931 and Pennsylva nia; Penn State University 814-863-7696 or University of Pennsylvania 610-444-5800.