A22-Lancaster Farming, Saturday, June 5, 1993 Treatment Considerations MICHAEL L. O’CONNOR PSU Dairy Extension STATE COLLEGE (Centre Co.) Uterine infection is a major problem on some dairy farms. Cows with uterine infections generally have lower conception rates and more days open. There has been considerable debate about the appropriate treatment for uterine infection. A multitude of antibiotics, dis infectants and hormones have been used to treat such infections. Some of these products have been shown to be ineffective, while others cause irritation, retard uter ine defense mechanisms, and may damage the lining of the reproduc tive system. The major uterine defense mechanism against bacterial infection is phagocytosis by leucocytes (white blood cells) within the uterus. Ovarian hor mones influence the ability of the uterus to eliminate bacterial infection. During the period when estro gen concentrations are elevated, uterine defense mechanisms are more effective, and thus the uterus is more resistant to infection. When a corpus luteum (CL) is pre sent and progesterone dominates the reproductive system, the uter us is more susceptible to infection. Take It Where You Need It! vnr©ifflK 36” Port-A-Fan® Quality Throughout Built For Service Built To Last The Moveable Solution! tuscarora electric MANUFACTURING COMPANY, INC. Tunkhannock, PA (717) 836-2101 FOR ALL YOUR I BUILDING NEEDS I * LUMBER * DOORS I * MILLWORK * PANELING I * TRUSES * INSULATION I * ROOFING * PLYWOOD I * WINDOWS * HARDWARE I * PAINT I [[ /X\ MUSSELMAN 1j I LUMBER, INC.JJ I 200 Brimmer Avenue I Rule New Holland, PA 17557 Rule I Lumber Lumber I c*** (717) 354-4321 _ Center [ II FAX (717) 355-2401 I The optimal therapy for uterine infection would be a treatment that does not inhibit natural uter ine defense mechanisms or cause adulteration of milk or meat, but eliminates pathogenic bacteria from the uterus. Most antibiotics and disinfec tants used for intrauterine therapy fail to meet some of these criteria. Prostaglandin (PG) is an effec tive alternative to antibiotic treat ment for most uterine infections. LAWRENCE W. SPECHT PSU Dairy Extension STATE COLLEGE (Centre Co.) Several indexes designed to evaluate the lifetime production and profitability of a cow have surfaced in the past year, includ ing the following: 1. Genetic evaluation for herd life may soon be available from USDA-AIPL. Herd life would be defined as “the cow’s total months of production, with a limit of 10 months per lactation.” No addi tional credit is given after a cow reaches seven years of age. Herita bility would be set at 8.5 percent (versus 25 percent for milk yield). USDA-AIPL says that the esti- Offered For Bovine Uterine Infections However, prostaglandin is a pre scription drug, and treatment for uterine infection is considered an extra label use. Justification for using PG is that it causes degeneration of the CL which lowers progesterone con centrations. Furthermore, once the CL degenerates, follicles continue development, and estrogen con centrations rise, uterine defense mechanisms are more effective, Determining Lifetime Profitability mated value of longevity could be included in total merit indexes such as production-type indexes or the USDA dollar value formula. Further research is needed to determine the value of herd life when other correlated traits such as udder height or somatic cell score are included in the index. 2. Lifetime Profitability Rank ing Dollars (LPRS) is “the amount of profit over a cow’s lifetime that you can expect from using a spe cific bull versus a breed average bull.” Profit is measured as net income over a cow’s lifetime and is based on herd life ratings which predict how many days of produc tive life a cow has in the herd after and smoother muscle contractions may expel uterine contaminants. Will PG treatment be effective for uterine infections which occur in the early postpartum period prior to formation of the first CL? Although a few trials have noted some benefits of PG treat ment in non-cycling cattle during the early postpartum period, the results are not as convincing as using PG for infected cows known first calving. Combining herd life estimates with production traits of the daughters determines a sire’s LPRS index. The top eight sires from the AI unit using this index ranged in LPRS from $169 to $192. Sires with the highest pro duction values and the best type indexes on their progeny would obviously rank highest in such a system. 3. Canadian sires are ranked on a lifetime profitability index (LPI). The index includes fat and protein production as well as final classification, feet and leg, and mammary system scores. The LPI is calculated as: LPI = 6CSF+6P) + 4(3FC + 4MS + Tulpehocken YF Holds Anti-Theft Meeting SHARTLESVILLE (Berks trooper from the Hamburg bar- Co.) — The Young Farmers racks will discuss how farmers can group of the Tulpehocken Area protect their equipment and lives- School District will present a prog- tock fr° m thieves, ram at 7 p.m. Monday, June 7, “Several farmers I work with about protecting farm equipment have had their shops robbed,” Wil and animals from theft. ,iams said - addin 8 that theives The meeting is to be held at the and continue to steal from Paul Zimmerman farm, located fa ™crs. along Tulpehocken Road, west of mcedn B * s open to the publ- Shartlesville. ic and is to-be held in the bam at Zimmerman’s farm. The farm is the first one on the left, when traveling west on Tulpehocken Road from Old Rt. 22. Chris Williams, an agriculture instructor at the high school and advisor to the group said a state to be cycling. Based on the results of several field studies, the therapeutic use of PG consistently shows recovery and fertility rates equal to intrauterine antibacterial therapy. Furthermore, there is no potential milk residue problem. However, when cattle are severely ill with metritis, more extensive veterinary therapy is required. 2FL + CAP) ( F=fat, P=protein, FC-final classification score, MS=mammary system, FL=feet and legs and CAP-capacity) The key question is, “Are life time indexes better indicators of a cow’s productive efficiency and profitability than other presently used criteria such as total lifetime production and/or production per day of life?” Any individual or organization can construct an index of traits that they believe to be important to dairy cattle improvement. It is critical that the values (weights) assigned to the traits in an index are backed by adequate research data.