—LancdSter Farming,.Satiirday, June 5, 1976
58
Horse breeding problems eased
KALAMAZOO, Mich -
Horse breeding
management has entered a
new technological age with
the introduction of the first
agricultural prostaglandin
product in the United States.
Announced at a
Prostaglandins in
Agriculture Conference held
hear here in March by The
Upjohn Company, the in
troduction of Prostin F 2
alpha represents a major
breakthrough in phar
maceutical technology. This
prostaglandin product will
be used by veterinarians to
aid horse breeders in the
timing of estrus and
breeding management
problems.
According to Upjohn
researcher Dr. James
Lauderdale, Prostin F 2
alpha (PGF2a) influences
the time of estrus in cycling
mares. This action aids in
bringing most difficult-to
breed mares into estrus, and
also helps control timing of
estrus in normally cycling
mares for more efficient
breeding.
Prostaglandins are potent
substances believed to play a
hey role in cellular
metabolism and regulation
of many bodily functions.
They have attracted world
wide interest during recent
years because of the
Widespread effects different
prostaglandins have on
various body processes in
both humans and animals.
Prostaglandins regulate a
variety of bodily functions
including reproduction,
blood pressure, gastric
secretion, inflammatory
response to injury, hormone
action, and blood dotting.
Some researchers term
them the new “miracle
drugs” of the 1970’s and 80’s.
Upjohn has been a
worldwide leader in
research and development of
prostaglandin compounds,
and last year introduced
PGF2a into some in
ternational markets for
regulating estrous cycles in
both horses and cattle.
“Introducing of Prostin F 2
alpha in the United States
represents Upjohn’s first
step in developing these very
significant compounds for
use in what’s hoped to be a
wide range of animal health
applications,” adds Dr.
Robert Zimbelman, Upjohn
research manager.
Mares are regarded as one
Resource Recovery
Many communities are find
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ly, garbage-to-energy sys
tems are operating in more
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Another fifty communities
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recovery systems that mag
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rous metals - mainly steel
cans - are operating in
thirty communities The
cans are detmned, remelted
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chemical leaching process
to recover copper from low
grade ore and used in the
production of ferroalloys
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of the most difficult animals
to breed efficiently because
of the seasonal nature and
relatively variable length of
their estrous cycles. Ac
cording to Dr. John Sullivan,
American Breeders Service,
the great variability in the
normal reproductive per
formance of mares is a
major breeding problem.
Prostin F 2 alpha is in
jected intramuscularly and
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MF
Massey Ferguson
KELLER BROS.
Ridge Road
Perkasie PA
Ph: 215-257-5698
or 257-5864
LEBANON
VALLEY
IMPLEMENT
700 E Linden St.
Richland PA
Phone: [7l7] 166-2544
mares are usually detected
in estrus an average of
three to four days after the
injection, with ovulation
occurring about seven days
after injection. Mares can be
bred during the induced
estrus.
“The product offers horse
owners the method for a
planned breeding program,”
Lauderdale says. “With
difficult-to-breed mares and
HEITZMAN M.
EQUIPMENT,
Phone 12151458-5777
or [2ls] 458-8525
N. K.
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CO.
Maxatawny
Phone (215] 683-7252
normally cycling mares
showing a high response to
this compound, the timing
and detection of estrus no
longer has to be left to
chance.”
Lauderdale refers to
research conducted by
Upjohn and independent
scientists. Clinically
anestrus mares so that
pregnancy can be
established by breeding at
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M. WEAVER S. G. LEWIS
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North Grofftown Road
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312 Park Ave
Quarryville, PA Washington Boro, PA RDI, Orwigsburg, PA
Phone [7l7] 716-3521 Phone [7l7] 285-4844 Ph: [7l7] 943-2304
estrus detected within a few
days after treatment.”
After conducting research
on this new product, Dr.
Robert Kenney, University
of Pennsylvania animal
reproduction scientist,
concludes, “it appears at
this time that PGF2a holds
promise of being the most
effective drug in the arsenal
of the veterinarian in brood
mare practice.”
ANY OF THE FOLLOWING:
West Grove, PA
[2ls] 869-9440
869-2214
FARM SERVICE
Charlestown Rd.-
Prospectßd
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Pitman, PA
[7l7] 648-1120
PAUL J.
EICHERT
& SON
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