USDA Mineral Study Aims at Fighting Selenium Poisoning
How to combat selenium Agriculture scientists as part
poisoning, which causes death of an over-all study of trace
of 'Cattle and sheep in certain minerals as they relate to hu
areas of the country, is being nutrition
studied by U.S. Department of Previous research indicates
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that selenium toxicity can be
decreased in several ways and
that each protective agent acts
by its own peculiar mechanism
One method involves the
amino acid, methionine, which
when used with vitamin E de
creases selenium residues in the
organs
To verify the methionine
vitamin E action and learn
more about the way these two
compounds work together, a
team of scientists m the human
nutrition laboratories of
USDA’s Agricultural Research
Service made a senes of studies
based on the response of female
weanling albino rats to a diet
high in selenium supplemented
with methionine, vitamin E,
and/or certain antioxidants.
All rats were fed a basic pea
nut meal diet devoid of vita
min E and with 10 parts per
million selenium added. Some
received a methionine supple
ment while vitamin E was add
ed to the diet of others.
Additional rats were given a
supplement containing both
methionine (0.5 per cent) and
vitamin E at different levels
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(0 01 to 005 per cent), while
certain antioxidants weie sub
stituted for vitamin E in the
diets of other rat groups
Rats that received the selen
ium-peanut meal diet without a
supplement of methionine or
vitamin E showed moderate to
severe liver damage Addition
of either one alone had only a
slight beneficial effect
All combinations of methion
ine and vitamin E protected
against selenium poisoning with
the best protection seen at the
higher vitamin E levels
When certain fat soluble an
tioxidants were substituted for
vitamin E in the combination
methiomne/vitamm E supple
ment, animals were protected
in varying degrees The water
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soluble antioxidants, methjlene
blue and ascorbic acid (vitamin
C), were ineffective
Selenium is one of the essen
tial trace minerals When the
diet does not contain enough
of this element, animals may
develop certain degenei ative
conditions of the liver, pan
creas, or heart, depending on
the animal species Rats and
monkeys lose hair and chickens
lose their feathers.
Sheep and cattle must also
have a certain amount of the
mineral to piotect their off
spnng from “white muscle dis
ease” found in most sheep-rais
ing coutones and in many cat
tle-producing areas where soil
and pasture do not contain ade
quate selenium
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