12 1-nncnskT Kanninn. Saturday. November 8.191i0
• Marek's
(Continued fiom I’agc 1)
puultiv imlti’oli \ m (leoigu .ip
piosim.ildv I!i to —it million do!
1.11 s
Until icccnllv Iheu* wcie no
tests to detenu.lie whethei u
lloek of buds w.i> piescntlv in
feited oi had eve. been infected
with Maiek's disease Rcseaieh
woikeis in Kngland using the
agai {tel diffusion technique de
nionstiated a pieeipitm reaction
between seia fiom MD infected
birds and an antigen prepaied
fiom tissue culluie cells infect
ed with the MD agent They
found the piecipitating antibody
in the blood of dav-old chicks
fiom MD positive dams which
was piobablv due to passive tian
sfei thiough the egg. howevei.
it does not appeal that this anti
bodv offeis anv pi election again
st m'd
At the piesent time theie are
no means (on the market) to
conti ol Maiek's disease, however
until geneticists can develop a
more lesistant bird, new approa
ches for conti ol must be taken
Therefoie, the subject of this
paper is several possible means
for conti oiling Marek’s disease.
Controlled Exposure Using
Old Litter
Time, method and degree of
exposure to the Mareb’s agent, in
the opinion of Dr Don Davis and
Dr Frank Siccaidi are the keys
to successful vaccination Litter
seeding appears to be the simpl
est method ot controlled expos
ure. This litter is taken from
hens that aie shedding the virus
and if day-old chicks are um
foimly exposed and the dosage
is not too high, then they aie
able to overcome the disease
However, I would like to point
out that controlled exposure
could be dangeious (1) When
you do not know whether the
litter even contains the MD
agent and if it does then how
much do you have in the litter
(2) Does the exposing material
contain other, possible more
harmful, disease agents?
There is much evidence which
would indicate that reused litter
helps to reduce MD condemna
tions, however, there are other
reseaicheis with data which
would indicate that reused litter
does not lowei MD condemna
tions At the present time the
use of old litter to reduce MD
losses is confusing My sugges-
BUY OR RENT A
POST
HOLE DIGGER
2", 4", 6" or 8" Bits
4 Feet- Deep.
m*i*
‘V, ' s - '
< —****
X
't.
r>
u
ELI F. KING
Pond Rd., R. D. 1, Ronks, Pa,
Phone 768 3670
(2 miles Noithwest of
Intel couise)
tlon would lie if you aie having
high MI) losses and you have
nothing to lose then try it, but
if youi losses aie low then I
would siig test slaving awav fiom
the use of old Idlei foi MD ton
Mol
Immunization Against Marek's
Disease Using an Inactivated
and a I-ive Attenuated Virus
The Cl \ Isolate of MD has
been passed many times in cell
cultuie which lesulled :n me
loss of us oncogenic potential
for the chicken Birds inoculated
at day of age with the attenuated
vn us are protected when chal
lenged with infective plasma
This would offer further evi
dence that herpes-type virus is
the causative agent of MD.
Birds inoculated at day of age
with a “killed" virus prepara
tion aie also piotected when
challenged with infected plasma
It would appear that a live at
tenuated MD vaccine could be
made available in the near fu
tuie, however, whether the US
DA will allow a live virus vac
cine of this nature to be sold can
only be answered by the USDA
Controlled Exposure With
Infective Plasma
Of the 1,400 one-day-old chicks
of the parental population inject
ed with the GA isolate, 69% died
as a result of MD by 20 weeks of
age The mortality ranged from
51 to 93% foi sire families Peak
mortality occurred between 8
and 14 weeks postinoculation
The mortality in the males was
66%, while that of the female
was 74% Cole (1968) found that
the female White Leghorn was
more susceptible to inoculation
with the JM agent The MD mor
tality of the selected families
(1, 21, 28, 30) were 69, 61, 53,
and 55% respectively Four per
cent mortality was observed in
the control parental population,
all of which occurred after 14
weeks of age. There was no mor
tality attributable to MD in con
tiol families, 1, 28 and 30; how
ever, 3 birds in family 21 were
found to contain MD lesions
Agway Inc.
Monday Evening, Nov. 10, 1969
'*'~o
'<♦« *
1 200 gal of fuel oil 12 Inside-Outside
theimometer
2 Cook Set
3 1 pair Wolverine shoes
14 1 gal paint lemover
4 1 extension coid
15 cook set
5 1 gal eitei ioi paint , ,
16 1 gal outside paint
6 1 Va" dull A ,
17 25 lb Agway cleaner
7 Claw hammer
18 1 gal paint i emover
8 1 gal extei ioi paint
19 1 set jumper cables
9 Hi-mtensity light r
20 1 gal plastic roof cement
10 1 gal glazing compound
21 1 case motoi oil
11 50 gal gasoline
Annual Meeting
Farm & Home Center, 1383 Arcadia Road, Lane,
• Guest* Speaker Glenn E. Edick
• Reports on Operations
O Election of four member committeemen
• Vocal selections by the “Trebleaires”
DOOR PRIZES
REFRESHMENTS
The inoculation of the p.ueii
till population with the MD
agent should remove the most
susceptible individuals fiom the
In ceding population so lh.it they
would not eonti ibute offspimg
In the neM geneiation If the iv
spouse of the ACitß stock to
mjetf.on with the GA isolate has
.1 hoi liable basis, then the pio
gen> of the lemaming bieedeis
should be moie resistant to in
jection than those fiom unmjccl
ed families MoitaliU in the pio
geny of the inoculated parental
population was 26 8%, while that
ol the progeny from unmoculat
ed controls was 42 Bf/c8 f /c with the
peak mortality for both groups
of progeny occurring between 7
and 11 weeks postmoculation.
These differences were highly
significant, indicating that icsis
tance to MD in the progeny could
be obtained by inoculation of the
parental population if the cn
teuon was moitality Although
the total lesions of the progeny
fiom the inoculated parental
population were less than for the
uninoculated ones (42 5 vs.
52 2%), these differences were
of much smallei magnitude than
mortality and not significant.
Thus, in a selection program,
birds selected for resistance to
death, only, might show gross
lesions which would condemn
them on processing
Control of MD by Raising
Chicken in Positive
Pressurized Houses
This paper is presented in re
sponce to the widespread interest
in complete enviromental poul
try housing and to discuss how
four cardinal principles, (1)
strict sanitation, (2) isolation,
(3) air filtration and (4) posi
tive pressurized poultry house,
are utilized to control losses to
MD among birds.m an experi
mental poultry flock.
Appioximately 200 cockerels
of the 687 birds reared m the
filtered air, positive pressure
houses were necropsied for MD
examination during the 40 week
observation period None have
died of the disease and no signs
or lesions were observed in those
7:30 P.M
13 Hand saw
22 1-5 gal gasoline can
• Form Colondor
(Continued from Page 1)
7:30 1* M Agway Garden Spot
Annual Meeting. F.nm and
Home Center.
Wednesday, N«v. 12
12 13— Penns\ h.ini.i Voting
examined Vas.inat.on or medi
cation was not contemplated in
the design of this piojccl and
there has been no outbreak of
any disease The MD mortality
results of birds reared in the
above house and results of reai •
ing birds in a similarly construct
ed house without filtered air and
positive pressure.
Princep turns
weedy
alfalfa
into
alfalfa
again.
Spraying Princep™ SOW on dormant alfalfa this fall,
can give you better quality, high-yielding alfalfa
next year.
It can lengthen the life of your alfalfa stand, and make
your hay worth more. If you’ve got a weedy alfalfa
stand at least a year old, spray Princep and you'll cut
cleaner hay next year.
Smoketown, Pa.
Farmer Convention, Pent
Slate.
515 P M—Lincoln 4H Com
munily Capon Exhibit, Le
gion Hall. Kphrata.
045 P M Lancaster County
Holstein Banquet. Farm and
Home Center,
Friday, Nov. 14
14-15—Slate 4 H Horse Show,
Faim Show Bldg.. Hams*
buig.
6 45 P M. Lancaster County
Gueinsey Bleeders meet. Span*
jsh Restaurant. Quarryville.
With today’s prices, it seems
as though the nickel has gone
the way of all other buffaloes.
Phone 397-3539