Little Miss Muffffet C.C. Bowling Results University Park, Pa. Black widow spiders and cockroaches are helping scientists at The Pennsylvania State University to untangle the web of mystery surrounding nerve membrane operations. Using the adult female spider’s venom, Dr. Thomas Smyth, Jr,, associate professor of entomology, and his former graduate student, Dr. David Griffiths, have demonstrated that the venom’s action is similar in cockroaches and higher animals. Dr. Smyth explains that in previous studies conducted by other scientists with frogs and cats, the spider venom selectively destroyed specific parts of the animals’ nerve endings. In experiments with cockroaches, Dr. Smyth and Dr. Griffiths obtained similar results even though that insect’s nerves are chemically and functionally different from those of the higher animals. The experiments with cockroaches indicate that the venom’s action on nerve membrane is similar in widely disparate parts of the animal kingdom. The Smyth-Griffiths study is detailed in a paper, “Action of Black Widow Spider Venom at Insect Neuromuscular Junctions,” published recently in the journal, Toxicon. Currently, Dr. Smyth and Richard Ornberg, a graduate student in biophysics, are trying to separate the venom, a complex mixture of proteins, into its individual parts or fractions. Dr. Smyth says, “Having the purified venom fractions should help us to find out what it is about the nerve endings that makes them different from other membranes.” Ornberg has worked out the prodecure for separating the venom in collaboration with Dr. Allen W. Benton, associate professor of agriculture at Penn State. The procedure, an electrophoretic separation of the venom, has never been done before. Dr. Smyth emphasizes that black widow spider venom is “mainly a tool” in the study. The venom is gathered by freezing spiders reared in the laboratory and then removing the venom glands after the spiders thaw. Ornberg points out that they are “very careful with the spiders” which are never allowed out of their plastic containers. Dr. Smyth, who has been studying the black widow for over three years, says the spiders are rare but are sometimes found in places such as old stone walls. He explains that the spiders bite and inject their venom with their mouth parts. Although the victim may be very sick for several days, he adds, the bites are seldom fatal. “Fatalities are usually attributable to hypersensitivity or an allergic reaction,” he says. In order to avoid being bitten, Dr. Smyth advises, “Stay out of the spider’s favorite spots, dark corners, outhouses.” If you get bitten, he says, "Put on a constrictor bandage and immediately seek medical attention.” Although an antidote to the venom is available, Dr. Smyth sees improved methods of treatment for black widow spider poisoning as additional fallout from the research. November 8,1973 TEAM 1. No Names 2. Keglers 3. Beta Chi .4. “I -l” 5. XGl’s 6. Spoilers 7. Dinkledorfs 8. Kozak 9. New Names 10. Strike Outs 11. ITE 12. Alleycats (500 CLUB) 1. Ed Houser (Keglers) - 561 2. John Yee ( No Names) - 552 3. Jim Herbst (Keglers) - 523 4. Paul Heintzmann (XGl’s) - 522 5. Mike Vitale (Spoilers) - 512 6. John Pruzinsky ( No Names) - 510 7. Dave Kurowski ("IT!”) - 509 No Names (4) - New Names (0) Dinkledorfs (4) - ITE (0) Strike Outs (4) - Alleycats (0) XGl’s (4) - Kozak (0( Keglers (3) - Beta Chi (1) “IT!LL (2)-Spoilers (2) MEN’S INDIVIDIALS H.A. Ed Houser (Keglers) - 184 H.S. Mike Vitale (Spoilers) - 575 H. Paul Heintzman (XGI’S) - 215 (200 CLUB) I. Mike Citale (Spoilers) - 208 2. John Yee ( No Names) - 206 3. Dave Kurowski (“IT!”) - 200 WOMEN’S INDIVIDUALS H.A. Barb Keeler (Dinkledorfs) - 125 H.S. Phyllis Mashman (Dinkledorfs) - 416 H.G. Dee Hribovsky (Alleycats) - 157 Remember, last day for make up week is November 14, 1973. TEAM 1. No Names 2. Keglers 3. “IT!” 4. Spoilers 5. Beta Chi 5. XGl’s 7. New Names 8. Dinkledorfs 9. Strike Outs 10. Kozak 11. ITE 12. Alleycats Mike Citale (Spoilers) 550 John Pruzinsky (No Names) 534 Ed Houser ( Keglers) 521 Murray Sharp (No Names (504) Paul Heintzman (XGl’s) 502 No Names (4) - Beta Chi (0) New Names (4) - Kozak (0) Keglers (4) - Dinkledorfs (0) Spoilers (3) • Strike Outs (1) “IT!” (3) - XGl’s (1) ITE (3) - Alleycats (1) Ed Houser (Keglers) 207 Dave Kuroqsky ( “IT!”) 203 Mike Vitale (Spoilers) 200 H.A. Phyllis Mashman (Dinkledorfs) 123 H.S. Barb Keeler Dinkeldorfs) 430 H.G. Dee Hribovsky (Alleycats) 157,156 Last day for make-up week is November 14, 1973!!! ** * * Graduate Record Exam (GRE) Law School Admission Test (LSAT) Admissions Test for Graduate Study in Business (ATGSB) Jan. 26, ‘74 National Teachers Exam (NTE) College of Podiatry Admissions test (CPAT) October 24, 1973 Won Lost Percentage 13 3 0.813 11 5 0.688 10 6 -.625 9 7 0.563 8 8 0.500 6 10 0.375 6 10 0.375 5 11 0.313 5 11 0.313 2 14 0.125 1 15 0.063 ** * * October 31, 1973 WON 20 17 13 11 11 10 (500 CLUB) MEN’S INDIVIDUALS H.A. Ed. Houser (Keglers) 181 H.S. Mike Vitale (Spoilers) 575 H.G. Paul Heintzman (XGl’s) 215 (200 CLUB) WOMEN’S INDIVIDUALS Test Dates To Remember Dec. 8, ‘73 Jan. 19, ‘74 Dec. 15,‘73 Jan. 26, ‘74 Feb. 16, ‘74 The Students’ Voice Recreation Athletic News LOST PERCENTAGE 0 1.000 3 .850 7 .650 9 .550 9 .550 10 .500 11 .450 14 .300 14 .300 14 .300 15 .250 18 .100 Nov. 13, Dec. 27, Nov. 20, ‘73 Test of English as a Jan. 2, ‘74 Foreign Language (TOEFL) Nov. 23, ‘73 Dental Admission Testing Program (DATP) Jan. 4, ‘74 Jan. 3, ‘74 Applications for these examinations, as well as study guides for some of these tests are available on a two week loan basis, in the Counseling Jan. 30,‘74 Office, Wll7. FLAG FOOTBALL: Standings as of Wed., Oct. 24 Schaffer Rag Time REO Speed Wagon Loose Ends Brotherhood NADS X.G.l.’s Bender Bros. Alpha Omega Foul Balls P.S.E.A. FLAG FOOTBALL SCORES Thursday, Oct. 18 Rag Time - 25 Foul Balls - 0 Monday, Oct. 22: Loose Ends - 21 P.S.E.A. - 0 REO Speed Wagon Schaffer - 0 Brotherhood - 24 Foul Balls - 0 Alpha Omega - 20 NADS - 6 Tuesday, Oct. 23: X.G.l.’s - 20 Bender Bros. - 13 Wednesday, Oct. 24 Foul Balls - 18 Loose Ends - 13 NADS - 20 Bender Bros. - 14 Alpha Omega - 26 Brotherhood - 0 REO Speed Wagon - P.S.E.A. - 6 Thursday, Oct. 25 Rag Time - 34 Schaffer - 8 All the flag football games scheduled for Monday, October 29th were cancelled due to the weather. The team captains of each game that was rained out should check with Mr. Smitley for a re-scheduling time. *. v--rvja- WHIRLPOOL Whirlpool hours are from 8:00 a.m. to 5 p.m., Monday thru Friday. The whirlpool CANNOT BE operated without an attendant on duty. In cases of emergency during off hours, check with the campus nurse!! ALSO: The whirlpool cannot be used for any purpose unless the person / persons have had prior approval from the doctor or nurse. BASE GYM: Any faculty and/or staff who have free time around 4:00 p.m. each day are invited to the Base Gym for an “open gym” period. VARSITY BASKETBALL All basketball members are reminded that physicals must be completed at the earliest possible time in order to be on the team. Miller Analogy Tests (MAT’s) are administered, by appointment, in the Counseling Office, Wll7. RBge7 Football Jan 5, ‘74 Jan. 12, ‘74 Nov. 29,‘73 Dec. 17,‘73